Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8660973 | 1.00 | CYP1A2 (0.46) | CYP1A2CA1CA9AKR1C4AKR1C3 | |
| SCHEMBL31509049 | 0.95 | CYP1A2 (0.50) | CYP1A2CA1CA9AKR1C4AKR1C3 | |
| SCHEMBL30886698 | 0.95 | CYP1A2 (0.50) | CYP1A2CA1CA9AKR1C4AKR1C3 | |
| SCHEMBL29475331 | 0.85 | CYP1A2 (0.40) | CYP1A2CA1CA9AKR1C4AKR1C3 | |
| SCHEMBL919914 | 0.85 | CYP1A2 (0.40) | CYP1A2CA1CA9AKR1C4AKR1C3 | |
| SCHEMBL9389681 | 0.85 | CYP1A2 (0.40) | CYP1A2CA1CA9AKR1C4AKR1C3 | |
| SCHEMBL919912 | 0.85 | CYP1A2 (0.40) | CYP1A2CA1CA9AKR1C4AKR1C3 | |
| SCHEMBL2939421 | 0.85 | CYP1A2 (0.40) | CYP1A2CA1CA9AKR1C4AKR1C3 | |
| SCHEMBL9389685 | 0.85 | CYP1A2 (0.40) | CYP1A2CA1CA9AKR1C4AKR1C3 | |
| SCHEMBL27968096 | 0.81 | CYP1A2 (0.51) | CYP1A2CA1CA9PPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10801033-B2 | Recombinant polynucleotide involved in lactone synthesis and process for synthesis of lactones thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-10-13 | — | — | US | disclosed |
| US-20190153459-A1 | RECOMBINANT POLYNUCLEOTIDE INVOLVED IN LACTONE SYNTHESIS AND PROCESS FOR SYNTHESIS OF LACTONES THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2019-05-23 | — | — | US | disclosed |
| EP-3423474-A2 | A RECOMBINANT POLYNUCLEOTIDE INVOLVED IN LACTONE SYNTHESIS AND PROCESS FOR SYNTHESIS OF LACTONES THEREOF | Council of Scientific and Industrial Research (IN) | 2019-01-09 | — | — | EP | disclosed |
| WO-2017175241-A2 | A RECOMBINANT POLYNUCLEOTIDE INVOLVED IN LACTONE SYNTHESIS AND PROCESS FOR SYNTHESIS OF LACTONES THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-10-12 | — | — | WO | disclosed |
| EP-0578388-B1 | Fermentation process for preparing 10-hydroxy-C18-carboxylic acid and gamma-dodecalactone derivatives | INT FLAVORS & FRAGRANCES INC (US) | 1998-11-04 | — | — | EP | disclosed |