Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.52 |
| ▸ | CHRM5 known ✓ | P08912 | 2/20 | 0.52 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.52 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.52 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.52 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.52 |
| ▸ | TACR2 | P21452 | 3/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5817662 | 0.98 | TP53 (0.55) | KMT2ATP53MEN1CYP1A2CYP2D6 | |
| SCHEMBL5308349 | 0.98 | TP53 (0.55) | KMT2ATP53MEN1CYP1A2CYP2D6 | |
| SCHEMBL5296534 | 0.98 | TP53 (0.55) | KMT2ATP53MEN1CYP1A2CYP2D6 | |
| SCHEMBL5294907 | 0.98 | TP53 (0.55) | KMT2ATP53MEN1CYP1A2CYP2D6 | |
| SCHEMBL5286951 | 0.98 | TP53 (0.55) | KMT2ATP53MEN1CYP1A2CYP2D6 | |
| SCHEMBL5308259 | 0.98 | TP53 (0.55) | KMT2ATP53MEN1CYP1A2CYP2D6 | |
| SCHEMBL5285490 | 0.98 | TP53 (0.55) | KMT2ATP53MEN1CYP1A2CYP2D6 | |
| SCHEMBL5290239 | 0.98 | TP53 (0.55) | KMT2ATP53MEN1CYP1A2CYP2D6 | |
| SCHEMBL5296656 | 0.98 | TP53 (0.55) | KMT2ATP53MEN1CYP1A2CYP2D6 | |
| SCHEMBL5301137 | 0.98 | TP53 (0.55) | KMT2ATP53MEN1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5783710-A | INK JET PRINTING; SPRAYING HOT MELT DROPLETS ON PLASTIC OR FIBER | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-21 | — | — | US | disclosed |
| EP-0593923-B1 | Water-insoluble sulfur dyes, their preparation and their use | CASSELLA FARBWERKE MAINKUR AG (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5374302-A | Reacting a sulfur dyes with a a-halocarboxylic acid; recording ink | CASSELLA AG (DE) | 1994-12-20 | — | — | US | disclosed |
| EP-0593923-A1 | Water-insoluble sulfur dyes, their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-27 | — | — | EP | disclosed |
| EP-0380984-A1 | Liquid algicidal compositions | RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) | 1990-08-08 | — | — | EP | disclosed |