Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 3/20 | 0.64 |
| ▸ | KLK1 | P06870 | 2/20 | 0.64 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.64 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29697587 | 0.86 | SRD5A2 (0.55) | PRSS1KLK1TMPRSS2PARP10SRD5A2 | |
| SCHEMBL12199140 | 0.85 | PARP10 (0.62) | PARP10SRD5A2KMT2AMAPTTDP1 | |
| SCHEMBL725405 | 0.84 | PARP10 (0.77) | PRSS1PARP10KMT2AMAPTTDP1 | |
| SCHEMBL19924698 | 0.84 | PARP10 (0.61) | PARP10KMT2AMAPTTDP1L3MBTL1 | |
| SCHEMBL1546405 | 0.84 | PARP10 (0.61) | PARP10KMT2AMAPTTDP1L3MBTL1 | |
| SCHEMBL4905240 | 0.84 | KMT2A (0.62) | PARP10KMT2AMAPTTDP1L3MBTL1 | |
| SCHEMBL8210785 | 0.84 | PARP10 (0.61) | PARP10SRD5A2KMT2AMAPTTDP1 | |
| SCHEMBL10608864 | 0.84 | PARP10 (0.61) | PARP10KMT2AMAPTTDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL16050040 | 0.82 | PARP10 (0.74) | PRSS1PARP10KMT2AMAPTTDP1 | |
| SCHEMBL9663679 | 0.82 | PARP10 (0.81) | PRSS1PARP10KMT2AMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714606-A | OLIGONUCLEOTIDE HAVING RECEPTOR BINDING SITES; ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS, MEDICAL DIAGNOSIS | ISIS PHARMACEUTICALS, INC. (US) | 1998-02-03 | — | — | US | disclosed |
| EP-0739335-A4 | PYRROLIDINE-CONTAINING MONOMERS AND OLIGOMERS | ISIS PHARMACEUTICALS INC (US) | 1997-04-02 | — | — | EP | disclosed |
| EP-0739335-A1 | PYRROLIDINE-CONTAINING MONOMERS AND OLIGOMERS | ISIS PHARMACEUTICALS, INC. (US) | 1996-10-30 | — | — | EP | disclosed |
| WO-1995018792-A1 | PYRROLIDINE-CONTAINING MONOMERS AND OLIGOMERS | ISIS PHARMACEUTICALS, INC. (US) | 1995-07-13 | — | — | WO | disclosed |
| EP-0440995-B1 | Process for preparing 1-octene | SHELL INT RESEARCH (NL) | 1994-05-11 | — | — | EP | disclosed |
| EP-0440995-A1 | Process for preparing 1-octene | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-08-14 | — | — | EP | disclosed |
| US-5030792-A | Process for preparing 1-octene | SHELL OIL COMPANY (US) | 1991-07-09 | — | — | US | disclosed |
| US-4288364-A | REACTING A 3-/2-HYDROXYIMINOACETYLAMINO/-2-OXOAZETIDINE WITH AN ORGANIC CARBONATE OR ACYL HALIDE | CIBA-GEIGY CORPORATION (US) | 1981-09-08 | — | — | US | disclosed |
| EP-0005507-A1 | Process for the fragmentation of 3-(2-hydroxyimino-acetylamino)-2-oxo azetidin compounds and compounds obtained thereby | CIBA-GEIGY AG (CH) | 1979-11-28 | — | — | EP | disclosed |