Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 6/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.50 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.50 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8660445 | 1.00 | GRIN1 (0.50) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL8656991 | 0.79 | GRIN1 (0.48) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL8656990 | 0.79 | GRIN1 (0.48) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL8660746 | 0.78 | GRIN1 (0.54) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL11138604 | 0.72 | GRIN1 (0.49) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL11138596 | 0.72 | GRIN1 (0.49) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL9819851 | 0.71 | KCNN4 (0.47) | KCNN4ALDH1A1LMNAGAAMAPT | |
| SCHEMBL9819853 | 0.71 | KCNN4 (0.47) | KCNN4ALDH1A1LMNAGAAMAPT | |
| SCHEMBL22312956 | 0.70 | GRIN1 (0.65) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL8657476 | 0.70 | GRIN1 (0.50) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0875762-A2 | Immunogens for raising antibodies useful in methadone fluorescence polarization immunoassay | Abbott Laboratories (US) | 1998-11-04 | — | — | EP | disclosed |
| EP-0380019-B1 | Methadone fluorescence polarization immunoassay | ABBOTT LAB (US) | 1995-11-08 | — | — | EP | disclosed |
| EP-0662613-A1 | Immunogens for raising antibodies useful in methadone fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1995-07-12 | — | — | EP | disclosed |
| US-5073629-A | Haptens attached to immunogenic carrier; quantitative analysis , drugs testing | ABBOTT LABORATORIES (US) | 1991-12-17 | — | — | US | disclosed |
| EP-0380019-A2 | Methadone fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1990-08-01 | — | — | EP | disclosed |