Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 11/20 | 0.69 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.66 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.66 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.66 |
| ▸ | MMP3 | P08254 | 2/20 | 0.62 |
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19789098 | 0.83 | HDAC1 (0.97) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL741005 | 0.82 | HDAC1 (0.71) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL13525415 | 0.81 | HDAC1 (0.53) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL13525414 | 0.81 | HDAC1 (0.53) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL7045198 | 0.81 | PPARA (0.63) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL7045357 | 0.81 | HDAC1 (0.97) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL7047579 | 0.80 | HDAC1 (0.47) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL7044810 | 0.80 | HDAC1 (1.00) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL3383144 | 0.80 | HDAC1 (1.00) | HDAC1HDAC2HDAC6HDAC3HDAC4 | |
| SCHEMBL6390077 | 0.80 | HDAC1 (0.74) | HDAC1HDAC2HDAC6HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874808-A1 | BIPHENYL HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES | Abbott Laboratories (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997018188-A1 | BIPHENYL HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 1997-05-22 | — | — | WO | disclosed |