SCHEMBL8660776

SCHEMBL8660776

[CH2]C(C)CCOC(=O)C=C

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.55
ALDH1A1 P00352 4/20 0.54
TP53 P04637 3/20 0.54
HIF1A Q16665 3/20 0.54
CYP3A4 P08684 2/20 0.54
HSD17B10 Q99714 1/20 0.54
HPGD P15428 1/20 0.53
THRB P10828 2/20 0.44
MAPK1 P28482 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TDP1 Q9NUW8 2/20 0.36
ALOX15 P16050 1/20 0.34
LMNA P02545 1/20 0.34
CHRNB2 P17787 3/20 0.33
CHRNA4 P43681 3/20 0.33
ATM Q13315 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27987243 0.88 TSHR (0.61) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29550542 0.85 TSHR (0.63) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL34661 0.85 TSHR (0.63) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9103359 0.85 TSHR (0.57) TSHRALDH1A1TP53HIF1ACYP3A4
Ethylene SCHEMBL28783854 0.83 TSHR (0.61) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL27800524 0.83 TSHR (0.55) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL27800526 0.83 TSHR (0.55) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL27753438 0.83 TSHR (0.55) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL142522 0.83 TSHR (0.55) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL10337184 0.83 TSHR (0.58) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114573815-A Quick-crosslinking-curing MQ-type silicon resin and preparation method and application thereof 杭州师范大学 2022-06-03 CN claimed
CN-114409903-A Alpha-cyanoacrylate-acetoxy-ethylene-oxypropyl-terminated cross MDQ silicon resin and preparation and application thereof 杭州师范大学 2022-04-29 CN claimed
US-5645752-A Thixotropic magnetorheological materials LORD CORPORATION (US) 1997-07-08 US claimed
EP-0667029-A1 THIXOTROPIC MAGNETORHEOLOGICAL MATERIALS LORD CORPORATION (US) 1995-08-16 EP claimed
EP-0667029-A4 THIXOTROPIC MAGNETORHEOLOGICAL MATERIALS. LORD CORP (US) 1995-06-13 EP claimed
WO-1994010693-A1 THIXOTROPIC MAGNETORHEOLOGICAL MATERIALS LORD CORPORATION (US) 1994-05-11 WO claimed
CN-117098670-A Thermosensitive recording medium 日本制纸株式会社 2023-11-21 CN disclosed
CN-116669679-A Adhesive composition for photo-molded article 可乐丽则武齿科株式会社 2023-08-29 CN disclosed
CN-114786957-B Thermosensitive recording medium 日本制纸株式会社 2023-08-29 CN disclosed
WO-2023068201-A1 PIGMENT DISPERSION, PHOTOSENSITIVE RESIN COMPOSITION, CURED PRODUCT, BLACK MATRIX, AND IMAGE DISPLAY DEVICE 三菱ケミカル株式会社 2023-04-27 WO disclosed
CN-115210219-A Oxime ester photoinitiators 巴斯夫欧洲公司 2022-10-18 CN disclosed
CN-110244513-B Colored photosensitive composition, black photo spacer and color filter 三菱化学株式会社 2022-10-14 CN disclosed
WO-2022215712-A1 PHOTOSENSITIVE COLORED RESIN COMPOSITION, CURED PRODUCT, PARTITION WALL, ORGANIC ELECTROLUMINESCENT ELEMENT, IMAGE DISPLAY DEVICE AND COMPOUND 三菱ケミカル株式会社 2022-10-13 WO disclosed
CN-100432789-C Blue composition for color filter, and color image display device MITSUBISHI CHEM CORP (JP) 2008-11-12 CN disclosed
CN-101027348-A Compositions containing anthraquinone dyes HUNTSMAN ADV MAT SWITZERLAND (CH) 2007-08-29 CN disclosed
CN-1947057-A Blue composition for color filter, and color image display device MITSUBISHI CHEM CORP (JP) 2007-04-11 CN disclosed
CN-1906536-A Photosensitive resin composition, color filter and liquid crystal display MITSUBISHI CHEM CORP (JP) 2007-01-31 CN disclosed
CN-1906524-A Resin composition for liquid crystal panel, color filter using the same, and liquid crystal panel MITSUBISHI CHEM CORP (JP) 2007-01-31 CN disclosed
EP-0667029-B1 THIXOTROPIC MAGNETORHEOLOGICAL MATERIALS LORD CORP (US) 1998-09-23 EP disclosed
US-5645752-A Thixotropic magnetorheological materials LORD CORPORATION (US) 1997-07-08 US disclosed