Benzohydroxamate

Benzohydroxamate

SCHEMBL8660923

N.O=C(NO)c1ccccc1

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 12/20 0.95
HDAC6 Q9UBN7 10/20 0.95
HDAC1 Q13547 8/20 0.95
HDAC2 Q92769 5/20 0.95
HDAC3 O15379 1/20 0.95
CA12 O43570 1/20 0.95
CA1 P00915 1/20 0.95
IDO1 P14902 1/20 0.95
ALOX15 P16050 1/20 0.95
CA9 Q16790 1/20 0.95
HDAC7 Q8WUI4 1/20 0.95
HSD17B10 Q99714 1/20 0.95
NCOR2 Q9Y618 1/20 0.95

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzohydroxamate SCHEMBL133061 0.97 HDAC8 (1.00) HDAC8HDAC6HDAC1HDAC2HDAC3
SCHEMBL21755109 0.97 HDAC8 (1.00) HDAC8HDAC6HDAC1HDAC2HDAC3
Benzohydroxamate SCHEMBL28895973 0.97 HDAC8 (1.00) HDAC8HDAC6HDAC1HDAC2HDAC3
Benzohydroxamate SCHEMBL28299068 0.97 HDAC8 (1.00) HDAC8HDAC6HDAC1HDAC2HDAC3
Benzohydroxamate SCHEMBL5159232 0.95 HDAC8 (0.95) HDAC8HDAC6HDAC1HDAC2HDAC3
Benzohydroxamate SCHEMBL6419261 0.95 HDAC8 (0.95) HDAC8HDAC6HDAC1HDAC2HDAC3
Benzohydroxamate SCHEMBL21630417 0.95 HDAC8 (0.95) HDAC8HDAC6HDAC1HDAC2HDAC3
Benzohydroxamate SCHEMBL11881231 0.95 HDAC8 (0.95) HDAC8HDAC6HDAC1HDAC2HDAC3
Benzohydroxamate SCHEMBL11883624 0.95 HDAC8 (0.95) HDAC8HDAC6HDAC1HDAC2HDAC3
Benzohydroxamate SCHEMBL10875530 0.95 HDAC8 (0.95) HDAC8HDAC6HDAC1HDAC2HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0598034-B1 PRODUCTION OF PEPTIDE AMIDES AMYLIN PHARMACEUTICALS INC (US) 1998-11-04 EP claimed
EP-0598034-A4 PRODUCTION OF PEPTIDE AMIDES. AMYLIN PHARMACEUTICALS INC (US) 1995-06-07 EP claimed
EP-0598034-A1 PRODUCTION OF PEPTIDE AMIDES AMYLIN PHARMACEUTICALS, INC. (US) 1994-05-25 EP claimed
WO-1993002697-A1 PRODUCTION OF PEPTIDE AMIDES AMYLIN PHARMACEUTICALS, INC. (US) 1993-02-18 WO claimed
EP-0598034-B1 PRODUCTION OF PEPTIDE AMIDES AMYLIN PHARMACEUTICALS INC (US) 1998-11-04 EP disclosed
US-5503989-A USING AMMONIUM SOURCE AND CHYMOTRYPSIN AMYLIN PHARMACEUTICALS, INC. (US) 1996-04-02 US disclosed