Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 5/20 | 0.49 |
| ▸ | NSD3 | Q9BZ95 | 4/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
| ▸ | GABRE | P78334 | 1/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7727 | 0.92 | ADORA2A (0.47) | NSD2NSD3ADORA2ALMNAHPGD | |
| SCHEMBL30670834 | 0.92 | NSD2 (0.46) | NSD2NSD3ADORA2AGABRPGABRD | |
| SCHEMBL8248 | 0.92 | NSD2 (0.46) | NSD2NSD3ADORA2AGABRPGABRD | |
| SCHEMBL15689097 | 0.91 | ADORA2A (0.48) | NSD2NSD3ADORA2ALMNAHPGD | |
| SCHEMBL8148 | 0.88 | ADORA2A (0.50) | NSD2NSD3ADORA2ALMNAHPGD | |
| SCHEMBL8479 | 0.85 | ADORA2A (0.44) | NSD2NSD3ADORA2ALMNAHPGD | |
| SCHEMBL8598 | 0.82 | ADORA2A (0.51) | NSD2NSD3ADORA2ALMNAHPGD | |
| SCHEMBL30670897 | 0.82 | PI4KA (0.47) | NSD2NSD3ADORA2ALMNAEGFR | |
| SCHEMBL9193 | 0.82 | PI4KA (0.47) | NSD2NSD3ADORA2ALMNAEGFR | |
| SCHEMBL9366 | 0.81 | PIK3CD (0.54) | ADORA2ALMNAHPGDSMN1; SMN2PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496567-A2 | NOVEL BENZOPYRAN KINASE MODULATORS | Rhizen Pharmaceuticals S.A. (CH) | 2012-09-12 | — | — | EP | claimed |
| WO-2011055215-A2 | NOVEL KINASE MODULATORS | INCOZEN THERAPEUTICS PVT. LTD. (IN) | 2011-05-12 | — | — | WO | claimed |
| EP-4292596-A1 | METHOD AND COMBINATION FOR TREATING TUMORS | Curon Biopharmaceutical (Shanghai) Co., Limited (CN) | 2023-12-20 | — | — | EP | disclosed |