Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.61 |
| ▸ | HTR2A | P28223 | 4/20 | 0.61 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.51 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | SCN4A | P35499 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17373052 | 0.88 | SCN4A (0.50) | HRH1HTR2ATAAR1SCN4ADPP4 | |
| Hydrochloric Acid SCHEMBL28350804 | 0.86 | SCN4A (0.48) | HRH1HTR2ATAAR1SCN4ADPP4 | |
| SCHEMBL2781356 | 0.83 | DPP4 (0.55) | HRH1HTR2ATAAR1SCN4ADPP4 | |
| SCHEMBL2781359 | 0.83 | DPP4 (0.55) | HRH1HTR2ATAAR1SCN4ADPP4 | |
| SCHEMBL2784864 | 0.83 | DPP4 (0.55) | HRH1HTR2ATAAR1SCN4ADPP4 | |
| SCHEMBL11681727 | 0.83 | TAAR1 (0.43) | HRH1HTR2ATAAR1SCN4ADPP4 | |
| SCHEMBL3634229 | 0.82 | HRH1 (0.68) | HRH1HTR2ATAAR1SCN4ADPP4 | |
| SCHEMBL4851319 | 0.80 | SLC2A1 (0.50) | HRH1HTR2ASCN4ADPP4 | |
| SCHEMBL5729099 | 0.80 | SCN4A (0.48) | HRH1HTR2ASCN4ADPP4F2 | |
| SCHEMBL22570767 | 0.80 | SLC2A1 (0.50) | HRH1HTR2ASCN4ADPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2728564-B2 | — | — | 1998-03-18 | — | — | JP | claimed |
| EP-0657029-A4 | CALCIUM RECEPTOR ACTIVE MOLECULES. | NPS PHARMA INC (US) | 1996-02-07 | — | — | EP | claimed |
| EP-0657029-A1 | CALCIUM RECEPTOR ACTIVE MOLECULES | NPS PHARMACEUTICALS, INC. (US) | 1995-06-14 | — | — | EP | claimed |
| WO-1993004373-A1 | CALCIUM RECEPTOR ACTIVE MOLECULES | NPS PHARMACEUTICALS, INC. (US) | 1993-03-04 | — | — | WO | claimed |