Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664839 | 0.93 | CYP3A4 (0.50) | CYP3A4CYP19A1CYP11B1CYP11B2LMNA | |
| SCHEMBL8662192 | 0.84 | CYP3A4 (0.53) | CYP3A4CYP19A1CYP11B1CYP11B2LMNA | |
| SCHEMBL8663731 | 0.82 | CYP3A4 (0.49) | CYP3A4CYP19A1CYP11B1CYP11B2LMNA | |
| SCHEMBL8664103 | 0.80 | CYP3A4 (0.58) | CYP3A4CYP19A1CYP11B1CYP11B2LMNA | |
| SCHEMBL9253548 | 0.77 | CYP3A4 (0.53) | CYP3A4CYP19A1CYP11B1CYP11B2LMNA | |
| SCHEMBL8757743 | 0.74 | CYP3A4 (0.55) | CYP3A4CYP19A1CYP11B1CYP11B2LMNA | |
| SCHEMBL9441203 | 0.72 | CYP3A4 (0.56) | CYP3A4CYP19A1CYP11B1CYP11B2LMNA | |
| SCHEMBL5899035 | 0.71 | CYP3A4 (0.63) | CYP3A4CYP19A1CYP11B1CYP11B2LMNA | |
| SCHEMBL9045971 | 0.71 | CYP3A4 (0.69) | CYP3A4CYP19A1CYP11B1CYP11B2LMNA | |
| SCHEMBL30944248 | 0.70 | CYP3A4 (0.53) | CYP3A4CYP19A1CYP11B1CYP11B2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707976-A | FUNGICIDES, 2-SILYLOXYPROPYLIMIDAZOLE OR TRIAZOLE | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1998-01-13 | — | — | US | claimed |
| US-5707976-A | FUNGICIDES, 2-SILYLOXYPROPYLIMIDAZOLE OR TRIAZOLE | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1998-01-13 | — | — | US | disclosed |