Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | PAOX | Q6QHF9 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.38 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15144969 | 1.00 | MAPT (0.64) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8661950 | 1.00 | MAPT (0.64) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9823545 | 1.00 | MAPT (0.64) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL16438106 | 1.00 | MAPT (0.64) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL31622243 | 1.00 | MAPT (0.64) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8661229 | 0.98 | — | — | |
| SCHEMBL1415148 | 0.90 | — | — | |
| SCHEMBL21661818 | 0.81 | PAOX (0.52) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL16288513 | 0.80 | MAPT (0.56) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9205295 | 0.80 | MAPT (0.56) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744666-A | Process for preparing an alkynyl fulvene group containing compound and said compound | PHILLIPS PETROLEUM COMPANY (US) | 1998-04-28 | — | — | US | claimed |
| US-5744666-A | Process for preparing an alkynyl fulvene group containing compound and said compound | PHILLIPS PETROLEUM COMPANY (US) | 1998-04-28 | — | — | US | disclosed |
| US-5728908-A | Process for preparing a bridged ligand and said bridged ligand | PHILLIPS PETROLEUM COMPANY (US) | 1998-03-17 | — | — | US | disclosed |
| US-5631203-A | Metallocene compounds and preparation thereof containing terminal alkynes | PHILLIPS PETROLEUM COMPANY (US) | 1997-05-20 | — | — | US | disclosed |