Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8662442 | 0.93 | HCAR2 (0.41) | HCAR2MAPT | |
| SCHEMBL9861013 | 0.81 | HCAR2 (0.33) | KEAP1NFE2L2HCAR2MAPTCACNA1B | |
| SCHEMBL9860291 | 0.81 | HCAR2 (0.33) | KEAP1NFE2L2HCAR2MAPTCACNA1B | |
| SCHEMBL9860300 | 0.75 | HCAR2 (0.42) | HCAR2MAPT | |
| SCHEMBL9861015 | 0.75 | HCAR2 (0.42) | HCAR2MAPT | |
| SCHEMBL9860304 | 0.75 | HCAR2 (0.42) | HCAR2MAPT | |
| SCHEMBL10557451 | 0.74 | HCAR2 (0.43) | HCAR2 | |
| SCHEMBL9350655 | 0.72 | MAPT (0.39) | MAPT | |
| SCHEMBL9727769 | 0.72 | HCAR2 (0.40) | HCAR2MAPT | |
| SCHEMBL28560682 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0580435-B1 | Diester monomer, its polymer, water-containing soft contact lens, and processing solution for contact lens | NOF CORP (JP) | 1998-09-16 | — | — | EP | disclosed |
| US-5466853-A | Diester monomer, its polymer, water-containing soft contact lens, and processing solution for contact lens | NOF CORPORATION (JP) | 1995-11-14 | — | — | US | disclosed |
| EP-0580435-A1 | Diester monomer, its polymer, water-containing soft contact lens, and processing solution for contact lens | NOF CORPORATION (JP) | 1994-01-26 | — | — | EP | disclosed |