Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655640 | 0.90 | EDNRB (0.77) | EDNRBEDNRA | |
| SCHEMBL8657137 | 0.86 | EDNRB (0.74) | EDNRBEDNRA | |
| SCHEMBL8656838 | 0.86 | EDNRB (0.76) | EDNRBEDNRA | |
| SCHEMBL2678965 | 0.85 | EDNRA (1.00) | EDNRBEDNRA | |
| SCHEMBL30057758 | 0.85 | EDNRA (1.00) | EDNRBEDNRA | |
| SCHEMBL8656334 | 0.84 | EDNRA (0.92) | EDNRBEDNRA | |
| Hydrochloric Acid SCHEMBL8658877 | 0.84 | EDNRB (0.82) | EDNRBEDNRA | |
| SCHEMBL21412548 | 0.84 | EDNRB (0.81) | EDNRBEDNRA | |
| SCHEMBL795853 | 0.83 | EDNRB (0.80) | EDNRBEDNRA | |
| SCHEMBL8659134 | 0.83 | EDNRB (0.76) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728706-A | ENDOTHELIN ANTAGONISTS | TANABE SEIYAKU CO., LTD. (JP) | 1998-03-17 | — | — | US | disclosed |
| EP-0658548-B1 | Benzenesulfonamide derivative and process for preparing thereof | TANABE SEIYAKU CO (JP) | 1997-11-19 | — | — | EP | disclosed |
| US-5589478-A | ENDOTHELIN ANTAGONISTS | TANABE SEIYAKU CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0658548-A1 | Benzenesulfonamide derivative and process for preparing thereof | TANABE SEIYAKU CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |