SCHEMBL8662885

SCHEMBL8662885

CCCCOc1nc(S)nc(S)n1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 2/20 0.38
CYP2D6 P10635 2/20 0.37
CYP3A4 P08684 1/20 0.37
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
LTA4H P09960 3/20 0.35
CYP1A2 P05177 3/20 0.34
CYP2C9 P11712 2/20 0.34
CYP2C19 P33261 2/20 0.34
NR5A1 Q13285 1/20 0.34
RAB9A P51151 5/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
HPGD P15428 2/20 0.34
TLR8 Q9NR97 1/20 0.34
LMNA P02545 1/20 0.34
POLB P06746 1/20 0.34
NPC1 O15118 4/20 0.33
HSD17B10 Q99714 2/20 0.33
KDM4E B2RXH2 2/20 0.33
CYP19A1 P11511 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22102113 0.94 MCHR1 (0.39) MCHR1LTA4HNR5A1TLR8CDK1
SCHEMBL22102115 0.92 MCHR1 (0.41) MCHR1LTA4HNR5A1TLR8CDK1
SCHEMBL22102114 0.92 MCHR1 (0.41) MCHR1LTA4HNR5A1TLR8CDK1
SCHEMBL22102111 0.92 MCHR1 (0.41) MCHR1LTA4HNR5A1TLR8CDK1
SCHEMBL22102178 0.86 HSD17B10 (0.35) MCHR1CYP1A2RAB9ATLR8LMNA
SCHEMBL598441 0.84 CYP2D6 (0.43) MCHR1CYP2D6CYP3A4PTGS1PTGS2
SCHEMBL19412780 0.78 MCHR1 (0.38) MCHR1CYP2D6CYP3A4PTGS1PTGS2
SCHEMBL899058 0.77 NR5A1 (0.43) MCHR1LTA4HNR5A1TLR8CDK1
SCHEMBL14971486 0.76 PDE4B (0.40) MCHR1CYP2D6CYP3A4PTGS1PTGS2
SCHEMBL25384494 0.75 NR5A1 (0.47) MCHR1LTA4HNR5A1TLR8CDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200192224-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2020-06-18 US disclosed
EP-0638594-B1 Chlorinated ethylene/alpha-olefin copolymer rubber and composition containing the same MITSUI CHEMICALS INC (JP) 1998-12-02 EP disclosed
US-5670551-A WET SUITS; CHLORINATED ETHYLENE-OLEFIN COPOLYMER, TRIAZINETHIOL, ALKYL AMMONIUM HALIDE, HYDROAZIDE BLOWING AGENT MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-09-23 US disclosed
EP-0453085-B1 Semiconductive rubber foam MITSUI PETROCHEMICAL IND (JP) 1997-01-08 EP disclosed
EP-0687705-A1 CROSS-LINKED FOAM AND PROCESS FOR PRODUCING THE SAME MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-12-20 EP disclosed
US-5470919-A Seals with ozone resistance, heat aging resistance, oil resistance and weatherproofing MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-11-28 US disclosed
EP-0453262-B1 Chlorinated ethylene-alpha-olefin copolymer rubber and composition thereof MITSUI PETROCHEMICAL IND (JP) 1995-09-06 EP disclosed
EP-0638594-A1 Chlorinated ethylene/alpha-olefin copolymer rubber and composition containing the same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-02-15 EP disclosed
US-5310818-A Vulcanizable chlorine-containing rubber compositions containing triazinethiol amine salt vulcanizing agents MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-05-10 US disclosed
US-5237010-A High vulcanization speed and improved heat resistance MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-08-17 US disclosed
EP-0292263-B1 VULCANIZABLE RUBBER COMPOSITION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-07-14 EP disclosed
US-5206305-A High speed vulcanization; heat resistance MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-04-27 US disclosed
US-5076967-A Chlorinated ethylene-alpha olefin copolymer, carbon black, cur ing and foaming agents MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-12-31 US disclosed
EP-0453262-A2 Chlorinated ethylene-alpha-olefin copolymer rubber and composition thereof MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-10-23 EP disclosed
EP-0453085-A2 Semiconductive rubber foam MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-10-23 EP disclosed
US-5004787-A With aliphatic or aromatic carboxylic acid amine salts or phenolic amine salts as promoters in chlorinated rubbers MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-04-02 US disclosed
EP-0292263-A2 Vulcanizable rubber composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-11-23 EP disclosed