Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7545435 | 0.89 | PDE10A (0.47) | PDE10AALOX5TP53MAPTNPC1 | |
| SCHEMBL8665167 | 0.86 | PDE10A (0.43) | PDE10ATP53MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8665024 | 0.85 | PDE10A (0.42) | PDE10AALOX5TP53MAPTSMN1; SMN2 | |
| SCHEMBL7548833 | 0.84 | PDE10A (0.47) | PDE10AALOX5TP53MAPTNPC1 | |
| SCHEMBL7544498 | 0.80 | PDE10A (0.43) | PDE10AALOX5MAPTALDH1A1HPGD | |
| SCHEMBL7549402 | 0.80 | PDE10A (0.43) | PDE10ATP53MAPTNPC1RAB9A | |
| SCHEMBL7542088 | 0.80 | PDE10A (0.44) | PDE10AALOX5NPC1RAB9AKDM4E | |
| SCHEMBL7548710 | 0.80 | PDE10A (0.44) | PDE10AALOX5TP53MAPTNPC1 | |
| SCHEMBL7541458 | 0.80 | PDE10A (0.44) | PDE10AALOX5MAOBTP53NPC1 | |
| SCHEMBL8668195 | 0.79 | NPC1 (0.53) | ALOX5MAPTNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736487-A | HERBICIDES | SANKYO COMPANY, LIMITED (JP) | 1998-04-07 | — | — | US | disclosed |