Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.44 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8662068 | 0.86 | GAA (0.50) | GAAKMT2AMEN1MAPTRAB9A | |
| SCHEMBL12877356 | 0.84 | GAA (0.70) | GAAKMT2AMEN1MAPTRAB9A | |
| SCHEMBL8666031 | 0.81 | GAA (0.48) | GAAKMT2AMEN1MAPTRAB9A | |
| SCHEMBL15387138 | 0.81 | GAA (0.53) | GAAKMT2AMEN1MAPTRAB9A | |
| SCHEMBL8663762 | 0.77 | GAA (0.56) | GAAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8291488 | 0.73 | GAA (0.67) | GAAKMT2AMEN1MAPTRAB9A | |
| SCHEMBL8663642 | 0.71 | GAA (0.46) | GAAKMT2AMEN1MAPTRAB9A | |
| SCHEMBL22198854 | 0.71 | GAA (0.50) | GAAKMT2AMEN1MAPTRAB9A | |
| SCHEMBL12114320 | 0.70 | GAA (0.61) | GAAKMT2AMEN1MAPTRAB9A | |
| SCHEMBL3407739 | 0.70 | GAA (0.40) | GAAKMT2AMEN1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876355-A1 | 2-THIOXO-IMIDAZOLIDIN-4-ONE DERIVATIVES AND THEIR USE FOR INCREASING HDL CHOLESTEROL CONCENTRATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-11-11 | — | — | EP | claimed |
| WO-1997019932-A1 | 2-THIOXO-IMIDAZOLIDIN-4-ONE DERIVATIVES AND THEIR USE FOR INCREASING HDL CHOLESTEROL CONCENTRATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-06-05 | — | — | WO | claimed |