SCHEMBL8664018

SCHEMBL8664018

COC(=O)CCCCCOC(=O)c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.69
LMNA P02545 4/20 0.56
TSHR P16473 2/20 0.50
LTB4R Q15722 1/20 0.49
ALDH1A1 P00352 2/20 0.48
NPC1 O15118 1/20 0.48
MAPT P10636 1/20 0.48
RAB9A P51151 1/20 0.48
AKT1 P31749 1/20 0.47
PPARG P37231 1/20 0.46
TBXAS1 P24557 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9796771 0.94 TDP1 (0.68) TDP1LMNATSHRALDH1A1AKT1
SCHEMBL14926467 0.86 TDP1 (0.51) TDP1LMNATSHRALDH1A1NPC1
SCHEMBL28595501 0.86 TSHR (0.66) TDP1LMNATSHRLTB4RALDH1A1
Methyl Benzoate SCHEMBL28780286 0.85 TSHR (0.70) TDP1LMNATSHRALDH1A1NPC1
SCHEMBL1172574 0.85 TDP1 (0.65) TDP1LMNATSHRALDH1A1NPC1
Alkyl (C12-15) Benzoate SCHEMBL27581023 0.85 TDP1 (0.65) TDP1LMNATSHRALDH1A1NPC1
SCHEMBL17466182 0.85 TDP1 (0.96) TDP1LMNATSHRALDH1A1NPC1
SCHEMBL11896606 0.85 TDP1 (0.96) TDP1LMNATSHRALDH1A1NPC1
SCHEMBL225815 0.85 TDP1 (0.96) TDP1LMNATSHRALDH1A1NPC1
SCHEMBL2069111 0.85 TDP1 (0.96) TDP1LMNATSHRALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012165550-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED ARTICLE THEREOF DIC株式会社 (JP) 2012-12-06 WO disclosed
EP-0455448-B1 Treatment of pancreatic disease with 15-keto-prostaglandin E compounds R TECH UENO LTD (JP) 1998-12-09 EP disclosed
EP-0503887-B1 Promotion of wound-healing with 15-keto-prostaglandin compounds R TECH UENO LTD (JP) 1996-08-28 EP disclosed
EP-0435443-B1 Use of 15-keto-prostaglandin compound for improvement of encephalic function R TECH UENO LTD (JP) 1996-08-28 EP disclosed
EP-0467564-B1 Treatment of inflammatory diseases with 15-keto-prostaglandin compounds R TECH UENO LTD (JP) 1996-04-24 EP disclosed
US-5426115-A Increasing blood stream rate in brain tissue KABUSHIKIKAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1995-06-20 US disclosed
US-5346921-A Treatment of inflammation with 15-keto-prostaglandin compounds R-TECH UENO, LTD. (JP) 1994-09-13 US disclosed
US-5290811-A Administering as antiischemic or antiedema agent; brain disorders, cognition activators KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1994-03-01 US disclosed
US-5252605-A Promotion of wound-healing with 15-keto-prostaglandin compounds R-TECH UENO LTD. (JP) 1993-10-12 US disclosed
US-5164415-A Amylase inhibitor K.K. UENO SEIYAKU OYO KENKYUJO (JP) 1992-11-17 US disclosed
EP-0503887-A2 Promotion of wound-healing with 15-keto-prostaglandin compounds R-TECH UENO LTD. (JP) 1992-09-16 EP disclosed
US-5117042-A 15-KETO-PROSTAGLANDIN COMPOUND FOR IMPROVEMENT OF ENCEPHALIC FUNCTION K.K. UENO SEIYAKU OYO KENKYUJO (JP) 1992-05-26 US disclosed
EP-0467564-A2 Treatment of inflammatory diseases with 15-keto-prostaglandin compounds R-TECH UENO LTD. (JP) 1992-01-22 EP disclosed
EP-0455448-A2 Treatment of pancreatic disease with 15-keto-prostaglandin compounds Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1991-11-06 EP disclosed
EP-0435443-A2 Use of 15-keto-prostaglandin compound for improvement of encephalic function R-TECH UENO LTD. (JP) 1991-07-03 EP disclosed