Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.31 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.31 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.31 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL667517 | 0.86 | CYP3A4 (0.62) | CYP3A4TRPA1MAPK1TDP1TSHR | |
| SCHEMBL141743 | 0.84 | CYP3A4 (0.50) | CYP3A4TRPA1MAPK1TDP1TSHR | |
| SCHEMBL14065577 | 0.84 | CYP3A4 (0.49) | CYP3A4TRPA1MAPK1TDP1TSHR | |
| SCHEMBL8596343 | 0.80 | CYP3A4 (0.55) | CYP3A4TRPA1MAPK1TDP1TSHR | |
| SCHEMBL543864 | 0.80 | CYP3A4 (0.55) | CYP3A4TRPA1MAPK1TDP1TSHR | |
| SCHEMBL10402481 | 0.79 | CYP3A4 (0.42) | CYP3A4TRPA1MAPK1TDP1TSHR | |
| SCHEMBL10651423 | 0.79 | CYP3A4 (0.42) | CYP3A4TRPA1MAPK1TDP1TSHR | |
| SCHEMBL18126138 | 0.78 | CYP3A4 (0.53) | CYP3A4TRPA1MAPK1TDP1TSHR | |
| SCHEMBL28464182 | 0.78 | CYP3A4 (0.44) | CYP3A4TRPA1MAPK1TDP1TSHR | |
| SCHEMBL29808709 | 0.78 | CYP3A4 (0.56) | CYP3A4TRPA1MAPK1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627452-B1 | UV-absorbing polyurethanes and polyesters | CIBA GEIGY AG (CH) | 1998-12-09 | — | — | EP | disclosed |
| US-5459222-A | UV-absorbing polyurethanes and polyesters | CIBA-GEIGY CORPORATION | 1995-10-17 | — | — | US | disclosed |
| EP-0627452-A1 | UV-absorbing polyurethanes and polyesters | CIBA-GEIGY AG (CH) | 1994-12-07 | — | — | EP | disclosed |