Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28927338 | 0.94 | BLM (0.55) | BLMLMNAACE2KDM4CKDM4A | |
| SCHEMBL3766286 | 0.91 | ACE2 (0.50) | BLMACE2PTPN1MEN1ALOX15 | |
| SCHEMBL16442960 | 0.87 | ACE2 (0.58) | ACE2PTPN1MEN1ALOX15KMT2A | |
| SCHEMBL243679 | 0.87 | ACE2 (0.58) | ACE2PTPN1MEN1ALOX15KMT2A | |
| SCHEMBL3284960 | 0.87 | ACE2 (0.58) | ACE2PTPN1MEN1ALOX15KMT2A | |
| SCHEMBL12474726 | 0.87 | ACE2 (0.58) | ACE2PTPN1MEN1ALOX15KMT2A | |
| SCHEMBL2695646 | 0.87 | ACE2 (0.58) | ACE2PTPN1MEN1ALOX15KMT2A | |
| SCHEMBL1720748 | 0.87 | ACE2 (0.58) | ACE2PTPN1MEN1ALOX15KMT2A | |
| SCHEMBL289584 | 0.87 | ACE2 (0.58) | ACE2PTPN1MEN1ALOX15KMT2A | |
| SCHEMBL3280815 | 0.87 | ACE2 (0.58) | ACE2PTPN1MEN1ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2439579-B1 | WETTABLE HYDROGEL CONTACT LENS AND METHOD FOR PRODUCING SAME | SEED CO LTD (JP) | 2018-11-07 | — | — | EP | disclosed |
| US-9329408-B2 | Wettable hydrogel contact lens and method for producing same | SEED CO., LTD. (JP) | 2016-05-03 | — | — | US | disclosed |
| US-20120074352-A1 | WETTABLE HYDROGEL CONTACT LENS AND METHOD FOR PRODUCING SAME | SEED CO., LTD. (JP) | 2012-03-29 | — | — | US | disclosed |
| EP-1806614-B1 | HIGHLY OXYGEN-PERMEABLE HYDRATED OCULAR LENS | SEED CO LTD (JP) | 2011-04-20 | — | — | EP | disclosed |
| US-7781536-B2 | Highly oxygen-permeable hydrated ocular lens | SEED CO., LTD. (JP) | 2010-08-24 | — | — | US | disclosed |
| US-20080094570-A1 | Highly Oxygen-Permeable Hydrated Ocular Lens | SEED CO., LTD. (JP) | 2008-04-24 | — | — | US | disclosed |
| EP-1806614-A1 | HIGHLY OXYGEN-PERMEABLE HYDRATED OCULAR LENS | Seed Co., Ltd. (JP) | 2007-07-11 | — | — | EP | disclosed |