Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8411443 | 0.95 | HTR1D (0.67) | HTR1DHTR1B | |
| SCHEMBL8661963 | 0.95 | HTR1D (0.58) | HTR1DHTR1B | |
| SCHEMBL8659333 | 0.95 | HTR1D (0.66) | HTR1DHTR1B | |
| SCHEMBL8699649 | 0.93 | HTR1D (0.63) | HTR1DHTR1B | |
| SCHEMBL8411686 | 0.92 | HTR1D (0.68) | HTR1DHTR1B | |
| SCHEMBL8410888 | 0.91 | HTR1D (0.67) | HTR1DHTR1B | |
| SCHEMBL8413944 | 0.89 | HTR1D (0.68) | HTR1DHTR1B | |
| SCHEMBL8664204 | 0.89 | HTR1D (0.59) | HTR1DHTR1B | |
| SCHEMBL8660431 | 0.89 | HTR1D (0.70) | HTR1DHTR1B | |
| SCHEMBL8414668 | 0.87 | HTR1D (0.67) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808064-A | HYDROSILATION OF AN INDOLE AS CHEMICAL INTERMEDIATE | MERCK & CO., INC. (US) | 1998-09-15 | — | — | US | claimed |
| US-5808064-A | HYDROSILATION OF AN INDOLE AS CHEMICAL INTERMEDIATE | MERCK & CO., INC. (US) | 1998-09-15 | — | — | US | disclosed |
| US-5807857-A | Piperazine, piperidine and tetrahydropyridine derivative of indol-3-alkyl as 5-HT1D-α agonists | MERCK SHARP & DOHME LTD. (GB) | 1998-09-15 | — | — | US | disclosed |