Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11548991 | 0.73 | — | — | |
| SCHEMBL11548988 | 0.73 | — | — | |
| SCHEMBL12534432 | 0.71 | — | — | |
| SCHEMBL2581155 | 0.71 | — | — | |
| SCHEMBL2338969 | 0.69 | — | — | |
| SCHEMBL5410206 | 0.68 | GABRR1 (0.34) | TSHR | |
| Fumaric Acid SCHEMBL3171992 | 0.68 | TSHR (0.60) | TSHRTP53EGLN1EGLN3HCAR2 | |
| Maleic Acid SCHEMBL6889391 | 0.68 | TSHR (0.60) | TSHRTP53EGLN1EGLN3HCAR2 | |
| Fumaric Acid SCHEMBL3171979 | 0.68 | TSHR (0.60) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL3698219 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0495603-B1 | Hydrogel material | PILKINGTON BARNES HIND INC (US) | 1998-10-14 | — | — | EP | claimed |