Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.58 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.58 |
| ▸ | PDE5A | O76074 | 7/20 | 0.56 |
| ▸ | PDE2A | O00408 | 1/20 | 0.56 |
| ▸ | PDE1A | P54750 | 1/20 | 0.56 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.56 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.56 |
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.55 |
| ▸ | HTR3A | P46098 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CCR4 | P51679 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7547470 | 0.99 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL7503592 | 0.91 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL7498058 | 0.90 | PDE5A (0.62) | PDE5APDE2A | |
| Hydrochloric Acid SCHEMBL7499545 | 0.86 | PDE11A (0.48) | PDE5APOLB | |
| SCHEMBL8170057 | 0.86 | PDE5A (0.48) | PDE5APOLB | |
| SCHEMBL8179227 | 0.86 | PDE5A (0.48) | PDE5APOLB | |
| SCHEMBL8183512 | 0.85 | PDE5A (0.47) | PDE5APOLB | |
| SCHEMBL4931286 | 0.85 | PDE4A (0.81) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| Hydrochloric Acid SCHEMBL7503522 | 0.84 | PDE4A (0.79) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL7129772 | 0.84 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801180-A | ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | EISAI CO., LTD. (JP) | 1998-09-01 | — | — | US | disclosed |