Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | F3 | P13726 | 1/20 | 0.50 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.50 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.50 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30518664 | 0.85 | GAA (0.47) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL5517164 | 0.85 | GAA (0.47) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL27701641 | 0.83 | GAA (0.46) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL5633185 | 0.82 | F7 (0.52) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL22251781 | 0.80 | CYP1A2 (0.46) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL1577273 | 0.79 | NOTUM (0.50) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL27677128 | 0.79 | F7 (0.48) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL525723 | 0.79 | F7 (0.48) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL28019723 | 0.79 | HTT (0.54) | F7F3SARM1SIRT2SIRT6 | |
| Pyridine SCHEMBL27731987 | 0.78 | F7 (0.38) | F7F3SARM1SIRT2SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646574-B1 | Ketonic indane derivatives, their preparation and therapeutic application thereof | INNOTHERA LAB SA (FR) | 1998-12-09 | — | — | EP | claimed |
| EP-0646574-A1 | Ketonic indane derivatives, their preparation and therapeutic application thereof | LABORATOIRE INNOTHERA Société Anonyme (FR) | 1995-04-05 | — | — | EP | disclosed |