Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | MET | P08581 | 2/20 | 0.41 |
| ▸ | PYGL | P06737 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665574 | 0.94 | KMT2A (0.51) | KMT2AMEN1POLBMAPTKDM4E | |
| SCHEMBL8658092 | 0.92 | KMT2A (0.52) | KMT2AMEN1POLBMAPTKDM4E | |
| SCHEMBL8659838 | 0.91 | KMT2A (0.53) | KMT2AMEN1POLBMAPTKDM4E | |
| SCHEMBL9720273 | 0.90 | KMT2A (0.47) | KMT2AMEN1POLBMAPTKDM4E | |
| SCHEMBL8658966 | 0.90 | KMT2A (0.47) | KMT2AMEN1POLBMAPTKDM4E | |
| SCHEMBL10492126 | 0.90 | KMT2A (0.48) | KMT2AMEN1POLBMAPTKDM4E | |
| SCHEMBL8660290 | 0.89 | MEN1 (0.46) | KMT2AMEN1POLBMAPTKDM4E | |
| SCHEMBL8659795 | 0.88 | KMT2A (0.49) | KMT2AMEN1POLBMAPTKDM4E | |
| SCHEMBL8658960 | 0.88 | KMT2A (0.49) | KMT2AMEN1POLBMAPTKDM4E | |
| SCHEMBL8660930 | 0.88 | MEN1 (0.49) | KMT2AMEN1POLBMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5420163-A | Insecticides or miticides | CIBA-GEIGY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |
| US-4873264-A | Novel pesticidal 1-(alkyl-phenoxy-aryl)-3-benzoyl ureas and process for preparation | RHONE-POULENC NEDERLANDS B.V. (NL) | 1989-10-10 | — | — | US | disclosed |
| EP-0098158-B1 | PESTICIDAL 1-(ALKYL-PHENOXYARYL)-3-BENZOYL UREAS AND PROCESS FOR PREPARATION | UNION CARBIDE CORPORATION (US) | 1987-11-19 | — | — | EP | disclosed |
| EP-0211004-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | RHONE-POULENC NEDERLAND B.V. (NL) | 1987-02-25 | — | — | EP | disclosed |
| WO-1986003941-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1986-07-17 | — | — | WO | disclosed |
| EP-0098158-A1 | Pesticidal 1-(alkyl-phenoxyaryl)-3-benzoyl ureas and process for preparation | UNION CARBIDE CORPORATION (US) | 1984-01-11 | — | — | EP | disclosed |