Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10770754 | 0.85 | ABCB1 (0.48) | ADRB3ABCB1HTTHIF1ATSHR | |
| SCHEMBL6017166 | 0.85 | ABCB1 (0.45) | ADRB3ABCB1HTTHIF1ATSHR | |
| SCHEMBL4480987 | 0.82 | TDP1 (0.45) | ADRB3TSHRPOLBTDP1KDM4E | |
| SCHEMBL6538543 | 0.79 | BACE1 (0.43) | ADRB3ABCB1POLBADRB1 | |
| SCHEMBL6540224 | 0.79 | BACE1 (0.43) | ADRB3ABCB1POLBADRB1 | |
| SCHEMBL7115615 | 0.77 | ADRB3 (0.62) | ADRB3ABCB1GAAPOLBMAPT | |
| SCHEMBL7116396 | 0.76 | ADRB3 (0.63) | ADRB3ABCB1MAPTNPSR1ADRB2 | |
| SCHEMBL7116378 | 0.76 | ADRB3 (0.63) | ADRB3MAPTNPSR1ADRB2ADRB1 | |
| SCHEMBL7115594 | 0.75 | ADRB3 (0.62) | ADRB3MAPTNPSR1ADRB2ADRB1 | |
| SCHEMBL7122900 | 0.75 | ADRB3 (0.62) | ADRB3MAPTNPSR1TDP1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767778-B1 | 1-PHENOXY-3-N-ALKYLAMINOPROPAN-2-OL HALOGEN DERIVATIVES USEFUL AS MYOCARDIAL beta ADRENERGIC RECEPTOR MARKERS AND AS beta-BLOCKING AGENTS | CIS BIO INT (FR) | 1998-12-16 | — | — | EP | disclosed |
| EP-0767778-A1 | 1-PHENOXY-3-N-ALKYLAMINOPROPAN-2-OL HALOGEN DERIVATIVES USEFUL AS MYOCARDIAL $g(b) ADRENERGIC RECEPTOR MARKERS AND AS $g(b)-BLOCKING AGENTS | CIS BIO INTERNATIONAL (FR) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000717-A1 | 1-PHENOXY-3-N-ALKYLAMINOPROPAN-2-OL HALOGEN DERIVATIVES USEFUL AS MYOCARDIAL β ADRENERGIC RECEPTOR MARKERS AND AS β-BLOCKING AGENTS | CIS BIO INTERNATIONAL (FR) | 1996-01-11 | — | — | WO | disclosed |