SCHEMBL8667709

SCHEMBL8667709

CCCCCCCCCCC[Si](OCC)(OCC)C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
THRB P10828 1/20 0.35
DNM1 Q05193 8/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 1/20 0.33
EPHX1 P07099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8667492 1.00 TSHR (0.35) TSHRTHRBDNM1MEN1KMT2A
SCHEMBL8669820 1.00 TSHR (0.35) TSHRTHRBDNM1MEN1KMT2A
SCHEMBL8669885 1.00 TSHR (0.35) TSHRTHRBDNM1MEN1KMT2A
SCHEMBL8165107 1.00 TSHR (0.35) TSHRTHRBDNM1MEN1KMT2A
SCHEMBL8669768 1.00 TSHR (0.35) TSHRTHRBDNM1MEN1KMT2A
SCHEMBL8667090 1.00 TSHR (0.35) TSHRTHRBDNM1MEN1KMT2A
SCHEMBL8669776 1.00 TSHR (0.35) TSHRTHRBDNM1MEN1KMT2A
SCHEMBL8666150 1.00 TSHR (0.35) TSHRTHRBDNM1MEN1KMT2A
SCHEMBL8668294 1.00 TSHR (0.35) TSHRTHRBDNM1MEN1KMT2A
SCHEMBL8667508 1.00 TSHR (0.35) TSHRTHRBDNM1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0530814-B1 Method for producing a stereospecific polyolefin TOSOH CORP (JP) 1998-12-16 EP disclosed
US-5489634-A EFFICIENT SELECTIVE CATALYTIC POLYMERIZATION OF ALPHA-OLEFINS YIELDS HIGH MOLECULAR WEIGHT SPHERICAL PARTICLES HAVING HIGH BULK DENSITY, CONTROLLED PARTICLE SIZE AND MOLECULAR WEIGHT DISTRIBUTION TOSOH CORPORATION (JP) 1996-02-06 US disclosed
EP-0582943-A2 Method for producing a polyolefin TOSOH CORPORATION (JP) 1994-02-16 EP disclosed
EP-0530814-A1 Method for producing a stereospecific polyolefin TOSOH CORPORATION (JP) 1993-03-10 EP disclosed