Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7494736 | 0.85 | PDE5A (0.63) | PDE5AKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL7495450 | 0.84 | PDE5A (0.68) | PDE5AKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL7500789 | 0.81 | PDE5A (0.67) | PDE5AKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL7491171 | 0.80 | PDE5A (0.71) | PDE5AKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL27528448 | 0.80 | PDE5A (0.65) | PDE5AKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL7497088 | 0.79 | PDE5A (0.72) | PDE5AKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL7498013 | 0.79 | PDE5A (0.67) | PDE5AKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL7491208 | 0.78 | PDE5A (0.71) | PDE5AKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL7495967 | 0.78 | PDE5A (0.67) | PDE5AKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL7504937 | 0.77 | PDE5A (0.68) | PDE5AKMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801180-A | ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | EISAI CO., LTD. (JP) | 1998-09-01 | — | — | US | disclosed |