Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 18/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962517 | 1.00 | ADRB3 (0.57) | ADRB3LMNAADRB2CHRM3ADRA1A | |
| SCHEMBL6913259 | 0.95 | ADRB3 (0.56) | ADRB3ADRB2CHRM3ADRA1A | |
| SCHEMBL6912580 | 0.95 | ADRB3 (0.56) | ADRB3ADRB2CHRM3ADRA1A | |
| SCHEMBL6912572 | 0.95 | ADRB3 (0.56) | ADRB3ADRB2CHRM3ADRA1A | |
| Hydrochloric Acid SCHEMBL7110385 | 0.94 | ADRB3 (0.55) | ADRB3ADRB2ADRA1A | |
| Hydrochloric Acid SCHEMBL7111083 | 0.94 | ADRB3 (0.55) | ADRB3ADRB2ADRA1A | |
| SCHEMBL7551009 | 0.92 | ADRB3 (0.49) | ADRB3LMNAADRB2CHRM3 | |
| SCHEMBL6913329 | 0.86 | ADRB3 (0.48) | ADRB3ADRB2CHRM3ADRA1A | |
| SCHEMBL6906532 | 0.86 | ADRB3 (0.48) | ADRB3ADRB2CHRM3ADRA1A | |
| SCHEMBL6906536 | 0.86 | ADRB3 (0.48) | ADRB3ADRB2CHRM3ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882707-A1 | NOVEL TRICYCLIC COMPOUNDS AND DRUG COMPOSITIONS CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1998-12-09 | — | — | EP | claimed |