Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | PSMB11 | A5LHX3 | 3/20 | 0.48 |
| ▸ | PSMA7 | O14818 | 3/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.48 |
| ▸ | PSMA1 | P25786 | 3/20 | 0.48 |
| ▸ | PSMA2 | P25787 | 3/20 | 0.48 |
| ▸ | PSMA3 | P25788 | 3/20 | 0.48 |
| ▸ | PSMA4 | P25789 | 3/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.48 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.48 |
| ▸ | PSMA5 | P28066 | 3/20 | 0.48 |
| ▸ | PSMB4 | P28070 | 3/20 | 0.48 |
| ▸ | PSMB6 | P28072 | 3/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.48 |
| ▸ | PSMB10 | P40306 | 3/20 | 0.48 |
| ▸ | PSMB3 | P49720 | 3/20 | 0.48 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.48 |
| ▸ | PSMA6 | P60900 | 3/20 | 0.48 |
| ▸ | PSMA8 | Q8TAA3 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15691256 | 0.84 | CYP1A1 (0.51) | CYP1A1MAOBPSMB11PSMA7PSMB1 | |
| SCHEMBL7890748 | 0.79 | CYP1A1 (0.55) | CYP1A1MAOBPSMB11PSMA7PSMB1 | |
| SCHEMBL10865344 | 0.76 | CYP1A1 (0.60) | CYP1A1MAOBPSMB11PSMA7PSMB1 | |
| SCHEMBL6832724 | 0.76 | CYP1A1 (0.71) | CYP1A1MAOBPSMB11PSMA7PSMB1 | |
| SCHEMBL27937384 | 0.76 | CYP1A1 (0.84) | CYP1A1MAOBPSMB11PSMA7PSMB1 | |
| SCHEMBL14075487 | 0.75 | MAPT (0.65) | CYP1A1MAOBPSMB11PSMA7PSMB1 | |
| SCHEMBL4337756 | 0.75 | PEPD (0.63) | CYP1A1MAOBPSMB11PSMA7PSMB1 | |
| SCHEMBL1929307 | 0.74 | CYP1A1 (0.62) | CYP1A1MAOBPSMB11PSMA7PSMB1 | |
| SCHEMBL10016246 | 0.73 | POLB (0.59) | CYP1A1MAOBPSMB11PSMA7PSMB1 | |
| SCHEMBL3659521 | 0.72 | CA1 (0.61) | CYP1A1MAOBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767778-B1 | 1-PHENOXY-3-N-ALKYLAMINOPROPAN-2-OL HALOGEN DERIVATIVES USEFUL AS MYOCARDIAL beta ADRENERGIC RECEPTOR MARKERS AND AS beta-BLOCKING AGENTS | CIS BIO INT (FR) | 1998-12-16 | — | — | EP | disclosed |
| EP-0767778-A1 | 1-PHENOXY-3-N-ALKYLAMINOPROPAN-2-OL HALOGEN DERIVATIVES USEFUL AS MYOCARDIAL $g(b) ADRENERGIC RECEPTOR MARKERS AND AS $g(b)-BLOCKING AGENTS | CIS BIO INTERNATIONAL (FR) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000717-A1 | 1-PHENOXY-3-N-ALKYLAMINOPROPAN-2-OL HALOGEN DERIVATIVES USEFUL AS MYOCARDIAL β ADRENERGIC RECEPTOR MARKERS AND AS β-BLOCKING AGENTS | CIS BIO INTERNATIONAL (FR) | 1996-01-11 | — | — | WO | disclosed |