Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6135196 | 0.97 | PTPN1 (0.36) | PTPN1PSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL27827735 | 0.97 | PTPN1 (0.36) | PTPN1PSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL23362295 | 0.95 | PTPN1 (0.39) | PTPN1PSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL28455936 | 0.95 | PTPN1 (0.39) | PTPN1PSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL19259364 | 0.95 | PTPN1 (0.39) | PTPN1PSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL6358420 | 0.90 | PTPN1 (0.37) | PTPN1 | |
| SCHEMBL23808213 | 0.87 | PTPN1 (0.45) | PTPN1FFAR4ACACBACACAFFAR1 | |
| SCHEMBL23772188 | 0.87 | PTPN1 (0.45) | PTPN1FFAR4ACACBACACAFFAR1 | |
| SCHEMBL22749505 | 0.87 | PTPN1 (0.45) | PTPN1FFAR4ACACBACACAFFAR1 | |
| SCHEMBL21965266 | 0.87 | PTPN1 (0.45) | PTPN1FFAR4ACACBACACAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811422-A | USEFUL FOR TREATING VIRAL INFECTIONS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-09-22 | — | — | US | disclosed |
| US-5610294-A | VIRAL TREATMENT | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-03-11 | — | — | US | disclosed |