Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 8/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | EP300 | Q09472 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613334 | 0.89 | HDAC1 (0.51) | HDAC4HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL12672579 | 0.82 | HDAC1 (0.70) | HDAC4HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL8585476 | 0.81 | HDAC4 (0.70) | HDAC4HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL27909125 | 0.80 | HDAC3 (0.64) | HDAC4HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL31091435 | 0.79 | EP300 (0.66) | HDAC4HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL1193343 | 0.79 | HDAC3 (0.62) | HDAC4HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL1233319 | 0.78 | CYP2C19 (0.82) | HDAC4HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL23048462 | 0.77 | CYP1A2 (0.67) | HDAC4HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL3138344 | 0.77 | CYP1A2 (0.62) | HDAC4HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL8587363 | 0.77 | HDAC1 (0.75) | HDAC4HDAC3HDAC1HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998031689-A1 | NOVEL MIXED BENZENE ACID DERIVATIVES, METHOD FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ADIR ET COMPAGNIE (FR) | 1998-07-23 | — | — | WO | disclosed |