⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2168948 | 0.91 | — | — | |
| SCHEMBL12131490 | 0.87 | — | — | |
| SCHEMBL17641593 | 0.82 | — | — | |
| SCHEMBL3425274 | 0.80 | — | — | |
| SCHEMBL5922482 | 0.80 | — | — | |
| SCHEMBL1504657 | 0.80 | — | — | |
| SCHEMBL5210273 | 0.80 | — | — | |
| SCHEMBL2749023 | 0.80 | — | — | |
| SCHEMBL336316 | 0.79 | — | — | |
| SCHEMBL24618196 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210355104-A1 | ADENOSINE RECEPTOR BINDING COMPOUNDS | NIKANG THERAPEUTICS, INC. (US) | 2021-11-18 | — | — | US | disclosed |
| US-8911710-B2 | Intravascular contrast agents | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-12-16 | — | — | US | disclosed |
| US-20110268663-A1 | INTRAVASCULAR CONTRAST AGENTS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2011-11-03 | — | — | US | disclosed |
| EP-0455448-B1 | Treatment of pancreatic disease with 15-keto-prostaglandin E compounds | R TECH UENO LTD (JP) | 1998-12-09 | — | — | EP | disclosed |
| EP-0435443-B1 | Use of 15-keto-prostaglandin compound for improvement of encephalic function | R TECH UENO LTD (JP) | 1996-08-28 | — | — | EP | disclosed |
| EP-0503887-B1 | Promotion of wound-healing with 15-keto-prostaglandin compounds | R TECH UENO LTD (JP) | 1996-08-28 | — | — | EP | disclosed |
| EP-0467564-B1 | Treatment of inflammatory diseases with 15-keto-prostaglandin compounds | R TECH UENO LTD (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5426115-A | Increasing blood stream rate in brain tissue | KABUSHIKIKAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1995-06-20 | — | — | US | disclosed |
| US-5346921-A | Treatment of inflammation with 15-keto-prostaglandin compounds | R-TECH UENO, LTD. (JP) | 1994-09-13 | — | — | US | disclosed |
| US-5290811-A | Administering as antiischemic or antiedema agent; brain disorders, cognition activators | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1994-03-01 | — | — | US | disclosed |
| US-5252605-A | Promotion of wound-healing with 15-keto-prostaglandin compounds | R-TECH UENO LTD. (JP) | 1993-10-12 | — | — | US | disclosed |
| US-5164415-A | Amylase inhibitor | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1992-11-17 | — | — | US | disclosed |
| EP-0503887-A2 | Promotion of wound-healing with 15-keto-prostaglandin compounds | R-TECH UENO LTD. (JP) | 1992-09-16 | — | — | EP | disclosed |
| US-5117042-A | 15-KETO-PROSTAGLANDIN COMPOUND FOR IMPROVEMENT OF ENCEPHALIC FUNCTION | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0467564-A2 | Treatment of inflammatory diseases with 15-keto-prostaglandin compounds | R-TECH UENO LTD. (JP) | 1992-01-22 | — | — | EP | disclosed |
| EP-0455448-A2 | Treatment of pancreatic disease with 15-keto-prostaglandin compounds | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1991-11-06 | — | — | EP | disclosed |
| EP-0435443-A2 | Use of 15-keto-prostaglandin compound for improvement of encephalic function | R-TECH UENO LTD. (JP) | 1991-07-03 | — | — | EP | disclosed |