Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.53 |
| ▸ | PPARD | Q03181 | 16/20 | 0.53 |
| ▸ | PPARG | P37231 | 15/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7041538 | 0.96 | PPARD (0.57) | PPARAPPARDPPARGNR1H2NR1H3 | |
| SCHEMBL7041527 | 0.92 | PPARA (0.61) | PPARAPPARDPPARGNR1H2NR1H3 | |
| SCHEMBL7042217 | 0.89 | PPARD (0.57) | PPARAPPARDPPARGNR1H2NR1H3 | |
| SCHEMBL7040338 | 0.84 | PPARD (0.54) | PPARAPPARDPPARGNR1H2NR1H3 | |
| SCHEMBL7042213 | 0.83 | PPARD (0.57) | PPARAPPARDPPARGNR1H2NR1H3 | |
| SCHEMBL7046138 | 0.83 | PPARD (0.61) | PPARAPPARDPPARGNR1H2NR1H3 | |
| SCHEMBL7040326 | 0.82 | PPARD (0.53) | PPARAPPARDPPARGNR1H2NR1H3 | |
| SCHEMBL7042917 | 0.81 | PPARD (0.73) | PPARAPPARDPPARGNR1H2NR1H3 | |
| SCHEMBL7039457 | 0.81 | PPARD (0.55) | PPARAPPARDPPARGNR1H2NR1H3 | |
| SCHEMBL7041536 | 0.76 | PPARD (0.57) | PPARAPPARDPPARGNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882029-A1 | HETEROCYCLIC DERIVATIVES AS ANTIDIABETIC AND ANTIOBESITY AGENTS | Merck & Co., Inc. (US) | 1998-12-09 | — | — | EP | disclosed |
| WO-1997028137-A1 | HETEROCYCLIC DERIVATIVES AS ANTIDIABETIC AND ANTIOBESITY AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | disclosed |