Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 7/20 | 0.54 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | NMBR | P28336 | 2/20 | 0.52 |
| ▸ | MMP1 | P03956 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3848569 | 0.92 | MEN1 (0.63) | MEN1KMT2AKCNA5BCHEALOX15 | |
| SCHEMBL3848966 | 0.92 | MEN1 (0.63) | MEN1KMT2AKCNA5BCHEALOX15 | |
| SCHEMBL3848969 | 0.92 | MEN1 (0.63) | MEN1KMT2AKCNA5BCHEALOX15 | |
| SCHEMBL8384762 | 0.91 | MEN1 (0.62) | MEN1KMT2AKCNA5BCHEACHE | |
| SCHEMBL8384759 | 0.91 | MEN1 (0.62) | MEN1KMT2AKCNA5BCHEACHE | |
| SCHEMBL6245120 | 0.91 | MEN1 (0.62) | MEN1KMT2AKCNA5BCHEACHE | |
| SCHEMBL6244061 | 0.91 | MEN1 (0.62) | MEN1KMT2AKCNA5BCHEACHE | |
| SCHEMBL6244059 | 0.91 | MEN1 (0.62) | MEN1KMT2AKCNA5BCHEACHE | |
| SCHEMBL6245123 | 0.91 | MEN1 (0.62) | MEN1KMT2AKCNA5BCHEACHE | |
| SCHEMBL28377319 | 0.91 | MEN1 (0.62) | MEN1KMT2AKCNA5BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708771-B1 | BENZYLOXYQUINUCLIDINES AS SUBSTANCE P ANTAGONISTS | PFIZER (US) | 1998-10-07 | — | — | EP | disclosed |