Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PPM1B | O75688 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14404525 | 1.00 | NPC1 (0.46) | NPC1ABCB1POLBPPM1B | |
| SCHEMBL7902225 | 1.00 | NPC1 (0.46) | NPC1ABCB1POLBPPM1B | |
| SCHEMBL24673848 | 0.94 | NPC1 (0.46) | NPC1ABCB1POLBPPM1B | |
| SCHEMBL22799541 | 0.94 | NPC1 (0.46) | NPC1ABCB1POLBPPM1B | |
| SCHEMBL23895298 | 0.93 | NPC1 (0.46) | NPC1POLBPPM1B | |
| SCHEMBL9851830 | 0.92 | NPC1 (0.48) | NPC1ABCB1POLBPPM1B | |
| SCHEMBL20938370 | 0.92 | NPC1 (0.48) | NPC1ABCB1POLBPPM1B | |
| SCHEMBL14404532 | 0.90 | NPC1 (0.46) | NPC1POLBPPM1B | |
| SCHEMBL1521263 | 0.90 | NPC1 (0.46) | NPC1POLBPPM1B | |
| SCHEMBL1521266 | 0.90 | NPC1 (0.46) | NPC1POLBPPM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130004979-A1 | GLYCOSYLTRANSFERASE REVERSIBILITY FOR SUGAR NUCLEOTIDE SYNTHESIS AND MICROSCALE SCANNING | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-01-03 | — | — | US | disclosed |
| US-5811512-A | BINDING TO G-PROTEIN-LINKED RECEPTORS, SUBSTANCE P RECEPTOR; HORMONE INHIBITORS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1998-09-22 | — | — | US | disclosed |