Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 10/20 | 0.66 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.66 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.66 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.66 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CASP7 | P55210 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MDM4 | O15151 | 1/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.52 |
| ▸ | VDR | P11473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL9068975 | 0.99 | GPBAR1 (0.65) | GPBAR1NR1H4PDE3ATBXA2RSLC10A2 | |
| Potassium Ion SCHEMBL9070343 | 0.91 | GPBAR1 (0.54) | GPBAR1NR1H4PDE3ATBXA2RSLC10A2 | |
| SCHEMBL9069691 | 0.91 | GPBAR1 (0.54) | GPBAR1NR1H4PDE3ATBXA2RSLC10A2 | |
| SCHEMBL9068995 | 0.91 | GPBAR1 (0.54) | GPBAR1NR1H4PDE3ATBXA2RSLC10A2 | |
| SCHEMBL9069673 | 0.89 | GPBAR1 (0.64) | GPBAR1NR1H4PDE3ATBXA2RSLC10A2 | |
| Ammonia Solution, Strong SCHEMBL9069311 | 0.88 | GPBAR1 (0.63) | GPBAR1NR1H4PDE3ATBXA2RSLC10A2 | |
| SCHEMBL3447484 | 0.88 | GPBAR1 (0.76) | GPBAR1NR1H4PDE3ATBXA2RSLC10A2 | |
| SCHEMBL21631677 | 0.88 | GPBAR1 (0.76) | GPBAR1NR1H4PDE3ATBXA2RSLC10A2 | |
| SCHEMBL21594795 | 0.88 | GPBAR1 (0.76) | GPBAR1NR1H4PDE3ATBXA2RSLC10A2 | |
| SCHEMBL7756845 | 0.88 | GPBAR1 (0.76) | GPBAR1NR1H4PDE3ATBXA2RSLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130336955-A1 | ANTIMICROBIAL FUSION COMPOUNDS AND USES THEREOF | VALIANT BIOPHARMA SDN BHD (MY) | 2013-12-19 | — | — | US | claimed |
| EP-2661451-A1 | ANTIMICROBIAL FUSION COMPOUNDS AND USES THEREOF | Valiant Biopharma SDN BHD (MY) | 2013-11-13 | — | — | EP | claimed |
| WO-2012093931-A1 | ANTIMICROBIAL FUSION COMPOUNDS AND USES THEREOF | VALIANT BIOPHARMA SDN BHD (MY) | 2012-07-12 | — | — | WO | claimed |
| US-5578304-A | Compositions of digestive enzymes and salts of bile acids and process for preparation thereof | DIGESTIVE CARE INC. (US) | 1996-11-26 | — | — | US | claimed |
| US-5415872-A | Buffers, bile salts, starches or cellulose and adhesives | DIGESTIVE CARE INC. (US) | 1995-05-16 | — | — | US | claimed |
| EP-2661451-B1 | ANTIMICROBIAL FUSION COMPOUNDS AND USES THEREOF | VALIANT BIOPHARMA SDN BHD (MY) | 2019-10-09 | — | — | EP | disclosed |
| US-20160068829-A1 | ANTIMICROBIAL FUSION COMPOUNDS AND USES THEREOF | VALIANT BIOPHARMA SDN BHD (MY) | 2016-03-10 | — | — | US | disclosed |
| US-9155800-B2 | Antimicrobial fusion compounds and uses thereof | VALIANT BIOPHARMA SDN BHD (MY) | 2015-10-13 | — | — | US | disclosed |
| US-20150284438-A1 | DOSAGE REGIME OF FUSION COMPOUNDS | BIOVALENCE SDN. BHD. (MY) | 2015-10-08 | — | — | US | disclosed |
| US-20150202250-A1 | ANTICANCER TREATMENT | BIOVALENCE SDN. BHD. (MY) | 2015-07-23 | — | — | US | disclosed |
| EP-2864362-A1 | ANTICANCER TREATMENT | Biovalence Sdn. Bhd. (MY) | 2015-04-29 | — | — | EP | disclosed |
| EP-2864361-A1 | DOSAGE REGIME OF FUSION COMPOUNDS | Biovalence Sdn. Bhd. (MY) | 2015-04-29 | — | — | EP | disclosed |
| WO-2014003536-A9 | DOSAGE REGIME OF FUSION COMPOUNDS | BIOVALENCE SDN. BHD. (MY) | 2014-01-30 | — | — | WO | disclosed |
| WO-2014003536-A1 | DOSAGE REGIME OF FUSION COMPOUNDS | BIOVALENCE SDN. BHD. (MY) | 2014-01-03 | — | — | WO | disclosed |
| WO-2014003537-A1 | ANTICANCER TREATMENT | BIOVALENCE SDN. BHD. (MY) | 2014-01-03 | — | — | WO | disclosed |
| US-20130336955-A1 | ANTIMICROBIAL FUSION COMPOUNDS AND USES THEREOF | VALIANT BIOPHARMA SDN BHD (MY) | 2013-12-19 | — | — | US | disclosed |
| EP-2661451-A1 | ANTIMICROBIAL FUSION COMPOUNDS AND USES THEREOF | Valiant Biopharma SDN BHD (MY) | 2013-11-13 | — | — | EP | disclosed |
| WO-2012093931-A1 | ANTIMICROBIAL FUSION COMPOUNDS AND USES THEREOF | VALIANT BIOPHARMA SDN BHD (MY) | 2012-07-12 | — | — | WO | disclosed |
| US-5750104-A | BUFFER ADDED FOR SIDE EFFECT REDUCTION WHILE MAINTAINING ENZYME ACTIVITY | DIGESTIVE CARE INC. (US) | 1998-05-12 | — | — | US | disclosed |
| US-5415872-A | Buffers, bile salts, starches or cellulose and adhesives | DIGESTIVE CARE INC. (US) | 1995-05-16 | — | — | US | disclosed |