Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 8/20 | 0.48 |
| ▸ | CCR3 | P51677 | 11/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674728 | 0.89 | TACR1 (0.56) | TACR1CCR3HRH3 | |
| SCHEMBL8670965 | 0.87 | TACR1 (0.48) | TACR1CCR3 | |
| SCHEMBL8675023 | 0.86 | CCR3 (0.52) | TACR1CCR3HRH3 | |
| SCHEMBL8675028 | 0.85 | TACR1 (0.51) | TACR1CCR3 | |
| SCHEMBL8673196 | 0.85 | CCR3 (0.53) | TACR1CCR3 | |
| SCHEMBL8673445 | 0.85 | CCR3 (0.50) | TACR1CCR3 | |
| SCHEMBL8672793 | 0.85 | CCR3 (0.55) | TACR1CCR3 | |
| SCHEMBL8671013 | 0.84 | TACR1 (0.54) | TACR1CCR3 | |
| SCHEMBL8669206 | 0.80 | TACR1 (0.45) | TACR1CCR3 | |
| SCHEMBL8673223 | 0.80 | TACR1 (0.61) | TACR1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708006-A | ANTIINFLAMMATORY AGENTS | BOEHRINGER INGELHEIM KG (DE) | 1998-01-13 | — | — | US | disclosed |
| US-5696123-A | ALPHA-PIPERAZINYL BENZYL COMPOUND AS TACHYKININ ANTAGONIST TREATING ASTHMA, BRONCHITIS, SKIN DISORDER, EYE DISEASE, HEADACHE, GASTROINTESTINAL DISORDER | BOEHRINGER INGELHEIM KG (DE) | 1997-12-09 | — | — | US | disclosed |