SCHEMBL867032

SCHEMBL867032

C=C(COCC(O)CO)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 5/20 0.38
TET3 O43151 1/20 0.38
TET1 Q8NFU7 1/20 0.38
USP2 O75604 1/20 0.36
KDM4E B2RXH2 3/20 0.33
LMNA P02545 3/20 0.33
DUSP3 P51452 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
GRIK1 P39086 1/20 0.32
GRIK2 Q13002 1/20 0.32
GRM1 Q13255 1/20 0.32
GRM2 Q14416 1/20 0.32
ALDH1A1 P00352 2/20 0.31
CYP1A2 P05177 2/20 0.30
OR51E2 Q9H255 1/20 0.30
AGTR1 P30556 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL10629812 0.98 TET2 (0.36) TET2TET3TET1USP2KDM4E
SCHEMBL7703243 0.84 TET2 (0.30) TET2TET3TET1
SCHEMBL17557844 0.82 USP2 (0.35) USP2KDM4ELMNADUSP3MEN1
Methacrylic Acid SCHEMBL29069600 0.79 USP2 (0.37) USP2KDM4ELMNADUSP3MEN1
Methacrylic Acid SCHEMBL28667287 0.79 USP2 (0.37) USP2KDM4ELMNADUSP3MEN1
SCHEMBL8608690 0.79 USP2 (0.41) USP2KDM4ELMNAMEN1KMT2A
SCHEMBL4332298 0.79 USP2 (0.41) USP2KDM4ELMNADUSP3MEN1
Methacrylic Acid SCHEMBL28359517 0.78 USP2 (0.41) TET2USP2KDM4ELMNADUSP3
Methacrylic Acid SCHEMBL28007405 0.78 USP2 (0.41) TET2USP2KDM4ELMNADUSP3
SCHEMBL18294831 0.75 TSHR (0.42) TET2TET3TET1KDM4EGRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 562 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3616703-B1 MOISTURIZING COMPOSITION OF A CONTACT LENS UNICON OPTICAL CO LTD (TW) 2022-02-09 EP claimed
US-10953614-B2 Moisturizing composition of a contact lens UNICON OPTICAL CO., LTD. (TW) 2021-03-23 US claimed
US-20200070451-A1 MOISTURIZING COMPOSITION OF A CONTACT LENS UNICON OPTICAL CO., LTD. (TW) 2020-03-05 US claimed
EP-3616703-A1 MOISTURIZING COMPOSITION OF A CONTACT LENS UNICON Optical Co, LTD. (TW) 2020-03-04 EP claimed
CN-110433269-A A kind of shaping detumescence gel and preparation method thereof HANGZHOU ZHONGHE SMART CITY TECH CO LTD 2019-11-12 CN claimed
CN-110368352-A A kind of pearl essence moisture retention liquid and preparation method thereof 陕西珍硒菁华科技研究院有限公司 2019-10-25 CN claimed
CN-110194877-A A kind of Nanometer composite hydrogel and its preparation method and application 湘潭大学 2019-09-03 CN claimed
EP-3502147-A1 COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS Merck Patent GmbH (DE) 2019-06-26 EP claimed
CN-109913071-A A kind of temperature control composite energy-saving material 中国科学院上海硅酸盐研究所 2019-06-21 CN claimed
CN-109846752-A A kind of collagen water light is against age facial mask and preparation method thereof 邱美玲 2019-06-07 CN claimed
US-5314961-A Acrylic-silicone polymers PERMEABLE TECHNOLOGIES, INC. (US) 1994-05-24 US claimed
US-5304334-A Method of preparing a multiphase composition ESTEE LAUDER, INC. (US) 1994-04-19 US claimed
US-5270415-A Balanced charge polymer and hydrophilic contact lens manufactured therefrom ALLERGAN INC. (US) 1993-12-14 US claimed
WO-1993021930-A1 METHOD OF PREPARING A MULTIPHASE COMPOSITION ESTEE LAUDER, INC. (US) 1993-11-11 WO claimed
EP-0563299-A1 BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM Hydron Limited (GB) 1993-10-06 EP claimed
US-5244981-A Acrylic polymers with pendant silicon containing groups, macromonomers, star polymers PERMEABLE TECHNOLOGIES, INC. (US) 1993-09-14 US claimed
EP-0552306-A1 NOVEL SILICONE-CONTAINING POLYMERS AND OXYGEN PERMEABLE HYDROPHILIC CONTACT LENSES THEREFROM PERMEABLE TECHNOLOGIES, INC. (US) 1993-07-28 EP claimed
US-5162469-A Copolymer of Fluoromonomer and Hydrophobic Hydrolyzable Silicone Monomer OPTICAL RESEARCH INC. (US) 1992-11-10 US claimed
WO-1992011301-A1 BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM ALLERGAN, INC. (US) 1992-07-09 WO claimed
WO-1992007013-A1 NOVEL SILICONE-CONTAINING POLYMERS AND OXYGEN PERMEABLE HYDROPHILIC CONTACT LENSES THEREFROM PERMEABLE TECHNOLOGIES, INC. (US) 1992-04-30 WO claimed