Oxirane

Oxirane

SCHEMBL8670366

C1CO1.CC(C)CCCCCOc1ccccc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.53
RARB P10826 1/20 0.50
HDAC3 O15379 1/20 0.49
HDAC4 P56524 1/20 0.49
HDAC1 Q13547 1/20 0.49
HDAC7 Q8WUI4 1/20 0.49
HDAC2 Q92769 1/20 0.49
HDAC10 Q969S8 1/20 0.49
HDAC11 Q96DB2 1/20 0.49
HDAC8 Q9BY41 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
HDAC9 Q9UKV0 1/20 0.49
HDAC5 Q9UQL6 1/20 0.49
HPGD P15428 1/20 0.48
LTA4H P09960 2/20 0.45
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
HTR1B P28222 1/20 0.43
TDP1 Q9NUW8 2/20 0.42
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11068531 0.91 KCNA3 (0.64) KCNA3RARBHDAC3HDAC4HDAC1
SCHEMBL12746095 0.91 KCNA3 (0.64) KCNA3RARBHDAC3HDAC4HDAC1
SCHEMBL358609 0.91 KCNA3 (0.64) KCNA3RARBHDAC3HDAC4HDAC1
SCHEMBL29394668 0.90 KCNA3 (0.61) KCNA3RARBHDAC3HDAC4HDAC1
SCHEMBL11580701 0.89 KCNA3 (0.67) KCNA3RARBHDAC3HDAC4HDAC1
Ethylene SCHEMBL28162451 0.88 KCNA3 (0.59) KCNA3RARBHDAC3HDAC4HDAC1
Ethylene Glycol SCHEMBL27943432 0.85 KCNA3 (0.55) KCNA3RARBHDAC3HDAC4HDAC1
SCHEMBL7449489 0.84 KCNA3 (0.62) KCNA3RARBHDAC3HDAC4HDAC1
SCHEMBL27936313 0.83 KCNA3 (0.53) KCNA3RARBHDAC3HDAC4HDAC1
SCHEMBL11818753 0.83 KCNA3 (0.53) KCNA3RARBHDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110102320-A A kind of hydrogen peroxide catalyzed dose of hollow palladium base of preparation method 贵州大学 2019-08-09 CN claimed
US-5817714-A USING A CYCLODIORGANOSILOXANE, SURFACTANT, WATER AND POLYMERIZATION CATALYST MIXTURE DOW CORNING CORPORATION (US) 1998-10-06 US claimed
CN-109675026-A Oil-based adjuvants 硕腾服务有限责任公司 2019-04-26 CN disclosed
CN-109675025-A Oil-based adjuvants 硕腾服务有限责任公司 2019-04-26 CN disclosed
CN-109675029-A Oil-based adjuvants 硕腾服务有限责任公司 2019-04-26 CN disclosed
CN-1978666-B Treatment solution for treating biological sample and method for detecting nucleic acid using treatment solution SYSMEX CORP 2012-05-30 CN disclosed
CN-1978666-A Treatment solution for treating biological sample and method for detecting nucleic acid using treatment solution SYSMEX CORP (JP) 2007-06-13 CN disclosed