Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.39 |
| ▸ | FDPS | P14324 | 9/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29064055 | 1.00 | TSHR (0.44) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL1018876 | 1.00 | TSHR (0.44) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL22449292 | 0.94 | TSHR (0.44) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL10535683 | 0.92 | TSHR (0.39) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL7253883 | 0.88 | TSHR (0.50) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL8716134 | 0.88 | TSHR (0.50) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL60278 | 0.88 | TSHR (0.35) | TSHRTHRBFDPS | |
| SCHEMBL28857305 | 0.88 | TSHR (0.50) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL28085782 | 0.88 | TSHR (0.50) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL9808555 | 0.88 | TSHR (0.50) | TSHRTHRBGGPS1FDPSSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612119-A | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents | 西雅图儿童医院（DBA西雅图儿童研究所） | 2019-12-24 | — | — | CN | claimed |
| CN-110325617-B | Surfactant for enhanced oil recovery | 道达尔公司 | 2022-07-08 | — | — | CN | disclosed |
| US-11254854-B2 | Surfactant for enhanced oil recovery | TOTALENERGIES SE (FR) | 2022-02-22 | — | — | US | disclosed |
| CN-110325617-A | SURFACTANT FOR ENHANCED OIL RECOVERY | 道达尔公司 | 2019-10-11 | — | — | CN | disclosed |
| US-5753649-A | Therapeutic agent for osteoporosis and diazepine compound | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5712274-A | ANTIINFLAMMATORY, ANTIALLERGEN | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-01-27 | — | — | US | disclosed |
| US-5593988-A | DIAZIPINE DERIVATIVES OF THIOPHENE FOR BONE DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0661284-A1 | THIENODIAZEPINE COMPOUND AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |
| EP-0638560-A1 | REMEDY FOR OSTEOPOROSIS AND DIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |
| US-4889944-A | Novel N-alkyl or N-alkenyl-N-(O,O-disubstituted-thio-phosphoryl)-N',N'-disubstituted glycin amides, process for the preparation thereof and acaricide, insecticide and fungicide containing these compounds as active ingredient | ESZAKMAGYARORSZAGI VEGYIMUVEK (HU) | 1989-12-26 | — | — | US | disclosed |