Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 19/20 | 0.68 |
| ▸ | AVPR1A | P37288 | 16/20 | 0.68 |
| ▸ | OXTR | P30559 | 1/20 | 0.58 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9028054 | 1.00 | AVPR2 (0.68) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL9028397 | 0.90 | AVPR1A (0.73) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL8670855 | 0.90 | AVPR1A (0.73) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL9028332 | 0.90 | AVPR1A (0.73) | AVPR2AVPR1AOXTRAVPR1B | |
| Hydrochloric Acid SCHEMBL9028238 | 0.90 | AVPR2 (0.62) | AVPR2AVPR1AOXTRAVPR1B | |
| Hydrochloric Acid SCHEMBL9028246 | 0.90 | AVPR2 (0.62) | AVPR2AVPR1AOXTRAVPR1B | |
| Hydrochloric Acid SCHEMBL9028876 | 0.89 | AVPR2 (0.69) | AVPR2AVPR1AOXTRAVPR1B | |
| Hydrochloric Acid SCHEMBL9028862 | 0.89 | AVPR2 (0.69) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL9029671 | 0.89 | AVPR1A (0.71) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL9029668 | 0.89 | AVPR1A (0.71) | AVPR2AVPR1AOXTRAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710150-A | ARGININE VASOPRESSIN ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0716083-A1 | BENZAZEPINE DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND INTERMEDIATE FOR THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-06-12 | — | — | EP | disclosed |