SCHEMBL8671536

SCHEMBL8671536

C=C[Si](C)(C)Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6897333 0.82
SCHEMBL8041110 0.78
SCHEMBL149858 0.70
SCHEMBL28824417 0.70
SCHEMBL191448 0.70
SCHEMBL4521329 0.67
SCHEMBL234500 0.67
SCHEMBL158463 0.67
SCHEMBL235771 0.67
SCHEMBL2060368 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3092264-B1 METHOD FOR CAPPING MQ-TYPE SILICONE RESINS DOW SILICONES CORP (US) 2019-10-23 EP claimed
US-9732191-B2 Method for capping MQ-type silicone resins DOW CORNING CORPORATION (US) 2017-08-15 US claimed
EP-3092264-A1 METHOD FOR CAPPING MQ-TYPE SILICONE RESINS Dow Corning Corporation (US) 2016-11-16 EP claimed
US-20160326320-A1 Method For Capping Mq-Type Silicone Resins DOW COMING CORPORATION (US) 2016-11-10 US claimed
WO-2015105931-A1 METHOD FOR CAPPING MQ-TYPE SILICONE RESINS DOW CORNING CORPORATION (US) 2015-07-16 WO claimed
EP-3768732-A1 PROCESS FOR FUNCTIONALIZATION OF ORGANO-ZINC COMPOUNDS WITH HALOSILANES USING BASIC NITROGEN CONTAINING HETEROCYCLES AND SILYL-FUNCTIONALIZED COMPOUNDS PREPARED THEREBY Dow Global Technologies LLC (US) 2021-01-27 EP disclosed
EP-3768733-A1 SILICON-TERMINATED TELECHELIC POLYOLEFIN COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME Dow Global Technologies LLC (US) 2021-01-27 EP disclosed
US-20210017311-A1 SILICON-TERMINATED TELECHELIC POLYOLEFIN COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC 2021-01-21 US disclosed
US-20210017195-A1 PROCESS FOR FUNCTIONALIZATION OF ORGANO-ZINC COMPOUNDS WITH HALOSILANES USING BASIC NITROGEN CONTAINING HETEROCYCLES AND SILYL-FUNCTIONALIZED COMPOUNDS PREPARED THEREBY DOW GLOBAL TECHNOLOGIES LLC (US) 2021-01-21 US disclosed
CN-111868109-A Method for functionalizing organozinc compounds with halosilanes using basic nitrogen-containing heterocycles and silane-functionalized compounds prepared therefrom 陶氏环球技术有限责任公司 2020-10-30 CN disclosed
CN-111868110-A Silicon-terminated telechelic polyolefin compositions and methods of making the same 陶氏环球技术有限责任公司 2020-10-30 CN disclosed
CN-104974184-B preparation of silazane Compounds 信越化学工业株式会社 2019-12-06 CN disclosed
US-5852153-A Trimethylsiloxy group-containing polysiloxane and a process for producing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-12-22 US disclosed
US-5693735-A Trimethylsiloxy group-containing polysiloxane and a process for producing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-12-02 US disclosed
US-4297458-A POLYEPOXIDES BY HEATING A DIGLYCIDYL ETHER, A CURE ACTIVATOR, AND A PHENYLSILANOL ACCELERATOR; SHELF LIFE GENERAL ELECTRIC COMPANY (US) 1981-10-27 US disclosed
US-4288603-A Silylated catechol compositions GENERAL ELECTRIC COMPANY (US) 1981-09-08 US disclosed
US-4273896-A Silylated polymers and silylated organic-organopolysiloxane block copolymers SWS SILICONES CORPORATION (US) 1981-06-16 US disclosed
US-4148838-A Silylated block copolymers SWS SILICONES CORPORATION (US) 1979-04-10 US disclosed
US-4143089-A SILYLATED POLYMERS SWS SILICONES CORPORATION (US) 1979-03-06 US disclosed
US-4080400-A Silylated polymers and silylated organic-organopolysiloxane block copolymers SWS SILICONES CORPORATION (US) 1978-03-21 US disclosed