Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | RARA | P10276 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 3/20 | 0.47 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668315 | 0.90 | PPARA (0.55) | KAT8PPARAMAPTPPARGGAA | |
| SCHEMBL1979931 | 0.86 | KAT8 (0.72) | KAT8PPARAMAPTPPARGRARB | |
| SCHEMBL10590574 | 0.86 | KAT8 (0.72) | KAT8PPARAMAPTPPARGRARB | |
| SCHEMBL2076751 | 0.85 | KAT8 (0.70) | KAT8PPARAMAPTPPARGRARB | |
| SCHEMBL10801712 | 0.85 | KAT8 (0.70) | KAT8PPARAMAPTPPARGRARB | |
| SCHEMBL8461758 | 0.83 | PPARA (0.72) | KAT8PPARAPPARGGAARARB | |
| SCHEMBL30697259 | 0.83 | PPARA (0.72) | KAT8PPARAPPARGGAARARB | |
| SCHEMBL4285667 | 0.83 | PPARA (0.72) | KAT8PPARAPPARGGAARARB | |
| SCHEMBL28330167 | 0.83 | PPARA (0.72) | KAT8PPARAPPARGGAARARB | |
| SCHEMBL31220575 | 0.83 | PPARA (0.72) | KAT8PPARAPPARGGAARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753649-A | Therapeutic agent for osteoporosis and diazepine compound | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5593988-A | DIAZIPINE DERIVATIVES OF THIOPHENE FOR BONE DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0638560-A1 | REMEDY FOR OSTEOPOROSIS AND DIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |