Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.56 |
| ▸ | USP2 | O75604 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | RGS12 | O14924 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 5/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.54 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.54 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8672555 | 0.85 | MEN1 (0.54) | MEN1KMT2AUSP2MAPTLMNA | |
| SCHEMBL8664259 | 0.84 | KDM4E (0.60) | MEN1KMT2AUSP2MAPTLMNA | |
| SCHEMBL8666679 | 0.81 | HEXA (0.51) | MEN1KMT2AMAPTKEAP1NFE2L2 | |
| SCHEMBL11256119 | 0.80 | MEN1 (0.65) | MEN1KMT2AUSP2MAPTLMNA | |
| SCHEMBL8664254 | 0.80 | HEXA (0.69) | MEN1KMT2AMAPTCYP1B1ALDH1A1 | |
| SCHEMBL8669762 | 0.80 | MEN1 (0.61) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL8668319 | 0.77 | HEXA (0.52) | MEN1KMT2AMAPTRECQLCYP1B1 | |
| SCHEMBL17583825 | 0.77 | MEN1 (0.64) | MEN1KMT2AUSP2MAPTLMNA | |
| SCHEMBL9006354 | 0.76 | MEN1 (0.68) | MEN1KMT2AUSP2MAPTLMNA | |
| SCHEMBL16213415 | 0.76 | HEXA (0.65) | MEN1KMT2AUSP2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789418-A | Bis-naphthalimides for the treatment of cancer | BASF AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |