⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11346359 | 0.90 | TSHR (0.41) | — | |
| SCHEMBL2225500 | 0.83 | — | — | |
| SCHEMBL26833 | 0.77 | TSHR (0.61) | — | |
| Cyclopropane Carboxylic Acid SCHEMBL5499291 | 0.77 | — | — | |
| Cyclopropane Carboxylic Acid SCHEMBL4643 | 0.77 | — | — | |
| Cyclopropane Carboxylic Acid SCHEMBL32889332 | 0.77 | — | — | |
| Cyclopropane Carboxylic Acid SCHEMBL10800712 | 0.77 | — | — | |
| SCHEMBL36093 | 0.77 | TSHR (0.61) | — | |
| SCHEMBL329128 | 0.77 | TSHR (0.61) | — | |
| SCHEMBL196124 | 0.77 | TSHR (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 574 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110582493-B | Benzoxazole derivatives as immunomodulators | 因赛特公司 | 2024-03-08 | — | — | CN | claimed |
| EP-4212529-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | Incyte Corporation (US) | 2023-07-19 | — | — | EP | claimed |
| EP-3774791-B1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORP (US) | 2022-12-21 | — | — | EP | claimed |
| CN-115413275-A | Substituted 1,1 , -biphenyl compounds and methods of use thereof | 爱彼特生物制药公司 | 2022-11-29 | — | — | CN | claimed |
| US-20220194931-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORPORATION | 2022-06-23 | — | — | US | claimed |
| CN-110177785-B | Dihydroisoquinoline compound | 苏州爱科百发生物医药技术有限公司 | 2022-02-08 | — | — | CN | claimed |
| US-20210380584-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORPORATION | 2021-12-09 | — | — | US | claimed |
| CN-110023315-B | Novel compound or pharmacologically acceptable salt thereof | 国立研究开发法人理化学研究所 | 2021-11-12 | — | — | CN | claimed |
| US-11124511-B2 | Heterocyclic compounds as immunomodulators | INCYTE CORPORATION (US) | 2021-09-21 | — | — | US | claimed |
| EP-3480198-B1 | NOVEL COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | RIKEN (JP) | 2021-05-05 | — | — | EP | claimed |
| EP-0791592-A2 | Azetidines | Pfizer Limited (GB) | 1997-08-27 | — | — | EP | claimed |
| EP-0775132-A1 | (AZETIDIN-1-YLALKYL)LACTAMS AS TACHYKININ ANTAGONISTS | Pfizer Limited (GB) | 1997-05-28 | — | — | EP | claimed |
| EP-0765865-A1 | 2-ACYLAMINOPROPANOL COMPOUND AND MEDICINAL COMPOSITION | SEIKAGAKU CORPORATION (JP) | 1997-04-02 | — | — | EP | claimed |
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | claimed |
| EP-0728759-A1 | Heterocyclic compounds | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-08-28 | — | — | EP | claimed |
| WO-1996005193-A1 | (AZETIDIN-1-YLALKYL)LACTAMS AS TACHYKININ ANTAGONISTS | PFIZER LIMITED (GB) | 1996-02-22 | — | — | WO | claimed |
| WO-1995004740-A1 | 7α-AMINO-1,1-DIOXOCEFEM L-VALYLAMIDES | DOMPE' S.P.A. (IT) | 1995-02-16 | — | — | WO | claimed |
| US-5021439-A | Senile dementia and memory dysfunction | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-06-04 | — | — | US | claimed |
| EP-0178845-A2 | Peptide-substituted heterocyclic immunostimulants | PFIZER INC. (US) | 1986-04-23 | — | — | EP | claimed |
| US-3983107-A | ARTERIOSCLEROSIS | PFIZER INC. (US) | 1976-09-28 | — | — | US | claimed |