Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.38 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.38 |
| ▸ | THPO | P40225 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 2/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | CASP2 | P42575 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | F13A1 | P00488 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL729525 | 0.86 | — | — | |
| SCHEMBL4377620 | 0.84 | ANPEP (0.38) | BLMDRD3LMNACYP3A4NFKB1 | |
| SCHEMBL28088005 | 0.84 | ANPEP (0.38) | BLMDRD3LMNACYP3A4NFKB1 | |
| SCHEMBL28858103 | 0.84 | ANPEP (0.38) | BLMDRD3LMNACYP3A4NFKB1 | |
| SCHEMBL2537119 | 0.84 | ANPEP (0.38) | BLMDRD3LMNACYP3A4NFKB1 | |
| Ammonia Solution, Strong SCHEMBL8502121 | 0.84 | ANPEP (0.38) | BLMDRD3LMNACYP3A4NFKB1 | |
| SCHEMBL29275122 | 0.84 | BLM (0.42) | BLMDRD3LMNACYP3A4NFKB1 | |
| SCHEMBL7163585 | 0.83 | CA12 (0.46) | BLMDRD3LMNACYP3A4NFKB1 | |
| SCHEMBL7759201 | 0.82 | ANPEP (0.36) | BLMDRD3LMNACYP3A4NFKB1 | |
| SCHEMBL6931739 | 0.82 | ANPEP (0.36) | BLMDRD3LMNACYP3A4NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824664-A | Suppression of HIV expression by organic thiophosphate | U.S. BIOSCIENCE, INC. (US) | 1998-10-20 | — | — | US | disclosed |
| WO-1994022307-A1 | SUPPRESION OF HIV EXPRESSION BY ORGANIC THIOPHOSPHATE | SCHEIN PHILIP A (US) | 1994-10-13 | — | — | WO | disclosed |