⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8673141 | 1.00 | — | — | |
| SCHEMBL6084738 | 0.78 | — | — | |
| SCHEMBL2118716 | 0.78 | — | — | |
| SCHEMBL8406605 | 0.77 | — | — | |
| SCHEMBL6082235 | 0.74 | — | — | |
| SCHEMBL2117792 | 0.74 | — | — | |
| SCHEMBL2118150 | 0.74 | — | — | |
| SCHEMBL7579046 | 0.72 | — | — | |
| SCHEMBL1760715 | 0.71 | — | — | |
| SCHEMBL6301594 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753649-A | Therapeutic agent for osteoporosis and diazepine compound | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5712274-A | ANTIINFLAMMATORY, ANTIALLERGEN | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-01-27 | — | — | US | disclosed |
| US-5593988-A | DIAZIPINE DERIVATIVES OF THIOPHENE FOR BONE DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0661284-A1 | THIENODIAZEPINE COMPOUND AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |
| EP-0638560-A1 | REMEDY FOR OSTEOPOROSIS AND DIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |