Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SPOP | O43791 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670569 | 0.94 | KDM4E (0.36) | KDM4ETSHRHSD17B10TDP1SPOP | |
| SCHEMBL8869474 | 0.94 | KDM4E (0.36) | KDM4ETSHRHSD17B10TDP1SPOP | |
| SCHEMBL8673687 | 0.87 | HSD17B10 (0.37) | KDM4ETSHRHSD17B10TDP1 | |
| SCHEMBL8868640 | 0.87 | HSD17B10 (0.37) | KDM4ETSHRHSD17B10TDP1 | |
| SCHEMBL8672280 | 0.85 | KDM4E (0.39) | KDM4ETSHRHSD17B10TDP1 | |
| SCHEMBL8672281 | 0.85 | KDM4E (0.39) | KDM4ETSHRHSD17B10TDP1 | |
| SCHEMBL8868772 | 0.85 | HSD17B10 (0.37) | KDM4ETSHRHSD17B10TDP1SPOP | |
| SCHEMBL8673723 | 0.85 | HSD17B10 (0.37) | KDM4ETSHRHSD17B10TDP1SPOP | |
| SCHEMBL8673308 | 0.80 | HSD17B10 (0.39) | KDM4ETSHRHSD17B10TDP1 | |
| SCHEMBL8673312 | 0.80 | HSD17B10 (0.39) | KDM4ETSHRHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789584-A | Substituted-pyridinyl cephalosporin antibiotics active against methicillin resistant bacteria | MICROCIDE PHARMACEUTICALS, INC. (US) | 1998-08-04 | — | — | US | disclosed |
| US-5756493-A | ACTIVE AGAINST METHICILLIN RESISTANT BACTERIA | MICROCIDE PHARMACEUTICALS, INC. (US) | 1998-05-26 | — | — | US | disclosed |
| US-5698547-A | 7-(ACYLAMINO)-3-(ARYLTHIO)-3-CEPHEM-4-CARBOXYLIC ACIDS WHICH EXHIBIT ANTIBACTERIAL ACTIVITY AGAINST ORGANISMS RESISTANT TO BETA-LACTAM ANTIBIOTICS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-12-16 | — | — | US | disclosed |
| US-5607926-A | ACTIVE AGAINST METHICILLIN RESISTANT BACTERIA | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-03-04 | — | — | US | disclosed |
| US-5604218-A | EXHIBITS ACTIVITY AGAINST METHICILLIN RESISTANT BACTERIA | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-02-18 | — | — | US | disclosed |
| EP-0754184-A1 | CEPHALOSPORIN ANTIBIOTICS | Microcide Pharmaceuticals, Inc. (US) | 1997-01-22 | — | — | EP | disclosed |
| US-5593986-A | Cephalosporin antibiotics | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-01-14 | — | — | US | disclosed |
| WO-1995026966-A1 | CEPHALOSPORIN ANTIBIOTICS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1995-10-12 | — | — | WO | disclosed |