Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.38 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.36 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8675926 | 0.99 | BRD4 (0.38) | BRD4CREBBPPDGFRBPDGFRABIRC5 | |
| Hydrochloric Acid SCHEMBL8679026 | 0.88 | BRD4 (0.36) | BRD4CREBBPPDGFRBPDGFRABIRC5 | |
| Hydrochloric Acid SCHEMBL8679084 | 0.87 | BRD4 (0.35) | BRD4CREBBPPDGFRBPDGFRABIRC5 | |
| Hydrochloric Acid SCHEMBL8674599 | 0.87 | BRD4 (0.36) | BRD4CREBBPPDGFRBPDGFRABIRC5 | |
| Hydrochloric Acid SCHEMBL8674408 | 0.87 | BRD4 (0.39) | BRD4CREBBPPDGFRBPDGFRABIRC5 | |
| Hydrochloric Acid SCHEMBL8675223 | 0.86 | BIRC5 (0.38) | BRD4CREBBPPDGFRBPDGFRABIRC5 | |
| Hydrochloric Acid SCHEMBL8675293 | 0.85 | AKR1C3 (0.36) | BRD4CREBBPPDGFRBPDGFRABIRC5 | |
| Hydrochloric Acid SCHEMBL8674683 | 0.85 | BRD4 (0.36) | BRD4CREBBPPDGFRBPDGFRABIRC5 | |
| SCHEMBL5953421 | 0.84 | PARP10 (0.37) | BRD4CREBBPPDGFRBPDGFRABIRC5 | |
| SCHEMBL7188601 | 0.82 | GSTP1 (0.36) | CYP1A2PFKFB3CYP2A6ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840947-A | Organometallic compound | TARGOR GMBH (DE) | 1998-11-24 | — | — | US | disclosed |