SCHEMBL8675859

SCHEMBL8675859

CC(C)(COCc1cccc(Oc2ccccc2)c1)c1ccc(OC(F)(F)F)cc1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 1/20 0.49
CETP P11597 10/20 0.46
TACR1 P25103 2/20 0.44
MRGPRX4 Q96LA9 2/20 0.43
NPC1 O15118 1/20 0.43
POLB P06746 1/20 0.43
CYP2C9 P11712 1/20 0.43
RAB9A P51151 1/20 0.43
NR3C1 P04150 1/20 0.41
LTA4H P09960 1/20 0.40
EPHX2 P34913 1/20 0.40
FFAR1 O14842 1/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10854916 0.94 NPC1 (0.43) MAPK14CETPTACR1NPC1POLB
Halfenprox SCHEMBL62803 0.93 NPC1 (0.43) MAPK14CETPTACR1NPC1POLB
Halfenprox SCHEMBL29795788 0.93 NPC1 (0.43) MAPK14CETPTACR1NPC1POLB
SCHEMBL10859391 0.91 NPC1 (0.49) CETPNPC1POLBCYP2C9RAB9A
SCHEMBL10856880 0.91 NPC1 (0.41) MAPK14CETPTACR1NPC1POLB
SCHEMBL8674911 0.91 NPC1 (0.41) MAPK14CETPTACR1NPC1POLB
SCHEMBL10849764 0.91 NPC1 (0.41) MAPK14CETPTACR1NPC1POLB
SCHEMBL9799184 0.90 NPC1 (0.44) MAPK14CETPNPC1POLBCYP2C9
SCHEMBL10849834 0.90 CETP (0.47) CETP
SCHEMBL9558335 0.89 TACR1 (0.48) MAPK14CETPTACR1MRGPRX4NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0543027-B1 INSECTICIDAL COMPOSITION AND PRODUCTION THEREOF MITSUI CHEMICALS INC (JP) 1998-11-18 EP disclosed
US-5733561-A PYRETHROID INSECTICIDE ENCAPSULATED IN MELAMINE-FORMALDEHYDE RESIN MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1998-03-31 US disclosed
EP-0543027-A1 INSECTICIDAL COMPOSITION AND PRODUCTION THEREOF MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-05-26 EP disclosed
EP-0257415-B1 INSECTICIDAL RESIN COATING FILM MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-03-31 EP disclosed
US-4997650-A (Meth)acrylonitrile polymer MITSUI TOATSU CHEMICALS, INC. (JP) 1991-03-05 US disclosed
US-4818525-A LONG-LASTING; ACRYLONITRILE COPOLYMER MITSUI TOATSU CHEMICALS, INC. (JP) 1989-04-04 US disclosed
EP-0257415-A1 Insecticidal resin coating film MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-03-02 EP disclosed